Medium-sized heterocycles are widespread among a spectrum of structurally intriguing and
biologically significant natural products and synthetic pharmaceuticals. Metal-catalyzed high …

Conspectus Asymmetric organocatalysis has been considered to be an efficient and reliable
strategy for the stereoselective preparation of optically active chemicals. In particular, chiral …

Herein, we report a synthesis of cyclohexanones bearing multi‐continuous stereocenters by
combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to cyclic …

The construction of acyclic, non‐adjacent 1, 3‐stereogenic centers, prevalent motifs in drugs
and bioactive molecules, has been a long‐standing synthetic challenge due to acyclic …

Metal‐polarized aza‐ortho‐quinone methides (aza‐o‐QMs) are a unique and efficient
handle for azaheterocycle synthesis. Despite great achievements, the potential of these …

We reported herein an iridium/silver/acid ternary catalytic system to access
bisbenzannulated [6, 6]‐spiroketals in high efficiency with generally high diastereo‐and …

The enantioselective cascade reaction between racemic 2‐(1‐hydroxyallyl) phenols and
alkynols/alkynamides was realized by using a gold and iridium sequential catalytic system …

Comprehensive Summary Cyclobutane derivatives have been recognized as useful
structural motifs in organic synthesis and drug design. With the revival of photochemistry, the …

Tetrasubstituted stereogenic carbon centers bearing a nitrogen substituent represent
important motifs in medicinal chemistry and natural products; therefore, the development of …

Medium-sized rings are important structural units in organic molecules of significant interest.
However, their efficient synthesis, especially in a highly enantioselective manner, has been …