Roles of miRNA and IncRNA in triple-negative breast cancer

J Xu, K Wu, Q Jia, X Ding - Journal of Zhejiang University-science b, 2020 - Springer
Triple-negative breast cancer (TNBC) is currently the most malignant subtype of breast
cancer without effective targeted therapies, which makes its pathogenesis an important …

Challenges and opportunities in developing targeted therapies for triple negative breast cancer

AG Chapdelaine, G Sun - Biomolecules, 2023 - mdpi.com
Triple negative breast cancer (TNBC) is a heterogeneous group of breast cancers
characterized by their lack of estrogen receptors, progesterone receptors, and the HER2 …

Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis

L Zhao, C Gu, Y Gan, L Shao, H Chen, H Zhu - Journal of Controlled …, 2020 - Elsevier
High recurrence and metastasis of triple-negative breast cancer (TNBC) after operation is a
leading cause of breast cancer related death. The pre-metastatic niche (PMN) is an …

Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer

P Du, H Zeng, Y Xiao, Y Zhao, B Zheng, Y Deng… - Cell death & …, 2020 - nature.com
Chronic stress could induce cancer metastasis by constant activation of the sympathetic
nervous system, while cellular mechanism remains obscure. The aim of this research is to …

Understanding patterns of brain metastasis in triple-negative breast cancer and exploring potential therapeutic targets

Y Lv, X Ma, Y Du, J Feng - OncoTargets and therapy, 2021 - Taylor & Francis
Triple-negative breast cancer (TNBC) is a highly malignant subtype of breast cancer. High
invasiveness and heterogeneity, as well as a lack of drug targets, are the main factors …

Current therapeutic approaches and promising perspectives of using bioengineered peptides in fighting chemoresistance in triple-negative breast cancer

M Azari, F Bahreini, VN Uversky, N Rezaei - Biochemical Pharmacology, 2023 - Elsevier
Breast cancer is a collation of malignancies that manifest in the mammary glands at the early
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …

Long noncoding RNAs in triple‐negative breast cancer: A new frontier in the regulation of tumorigenesis

KK Thakur, A Kumar, K Banik, E Verma… - Journal of cellular …, 2021 - Wiley Online Library
In recent years, triple‐negative breast cancer (TNBC) has emerged as the most aggressive
subtype of breast cancer and is usually associated with increased mortality worldwide. The …

Epigenetic alterations in triple-negative breast cancer—the critical role of extracellular matrix

V Zolota, V Tzelepi, Z Piperigkou, H Kourea… - Cancers, 2021 - mdpi.com
Simple Summary Current data suggest that epigenetic alterations are involved in the
initiation and subclonal evolution of breast cancer. During cancer progression, the …

Effective suppression of triple negative breast cancer by paclitaxel nanoparticles conjugated with transmembrane TNF-α monoclonal antibody

J Liu, P Wang, B Huang, Q Cheng, Y Duan… - International journal of …, 2022 - Elsevier
Abstract Transmembrane TNF-α (tmTNF), a transmembrane form of TNF-α, was reported
overexpressed in approximately 84% of triple-negative breast cancer (TNBC) patients and …

Function and inhibition of DYRK1A: emerging roles of treating multiple human diseases

Y Yang, X Fan, Y Liu, D Ye, C Liu, H Yang, Z Su… - Biochemical …, 2023 - Elsevier
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is an evolutionarily
conserved protein kinase and the most studied member of the Dual-specificity tyrosine …