Current status in spatiotemporal analysis of contrast‐based perfusion MRI

ES Shalom, A Khan, S Van Loo… - Magnetic resonance in …, 2024 - Wiley Online Library
In perfusion MRI, image voxels form a spatially organized network of systems, all
exchanging indicator with their immediate neighbors. Yet the current paradigm for perfusion …

[HTML][HTML] Image-based predictive modelling frameworks for personalised drug delivery in cancer therapy

A Bhandari, B Gu, FM Kashkooli, W Zhan - Journal of Controlled Release, 2024 - Elsevier
Personalised drug delivery enables a tailored treatment plan for each patient compared to
conventional drug delivery, where a generic strategy is commonly employed. It can not only …

In silico simulation: a key enabling technology for next-generation intelligent surgical systems

BD Killeen, SM Cho, M Armand… - Progress in …, 2023 - iopscience.iop.org
To mitigate the challenges of operating through narrow incisions under image guidance,
there is a desire to develop intelligent systems that assist decision making and spatial …

Towards integration of time-resolved confocal microscopy of a 3D in vitro microfluidic platform with a hybrid multiscale model of tumor angiogenesis

CM Phillips, EABF Lima, M Gadde… - PLoS Computational …, 2023 - journals.plos.org
The goal of this study is to calibrate a multiscale model of tumor angiogenesis with time-
resolved data to allow for systematic testing of mathematical predictions of vascular …

Systematic evaluation of MRI-based characterization of tumor-associated vascular morphology and hemodynamics via a dynamic digital phantom

C Wu, DA Hormuth, T Easley, F Pineda… - Journal of Medical …, 2024 - spiedigitallibrary.org
Purpose Validation of quantitative imaging biomarkers is a challenging task, due to the
difficulty in measuring the ground truth of the target biological process. A digital phantom …