The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …

Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60–
90%. HCMV is the leading cause of congenital infections and poses a great health risk to …

For treatment and diagnosis of cancer, antibodies have proven their value and now serve as
a first line of therapy for certain cancers. A unique class of antibody fragments called …

Photodynamic therapy (PDT) is a promising cancer treatment which involves a
photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which …

Nanobodies are antibody fragments derived from camelids, naturally endowed with
properties like low molecular weight, high affinity and low immunogenicity, which contribute …

Highlights•Viral infections cause approximately 12% of all human cancers.•Viral cancers
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …

Asthma is a heterogeneous inflammatory disease of the airways that is associated with
airway hyperresponsiveness and airflow limitation. Although asthma was once simply …

It is well-established that infections with viruses harboring oncogenic potential increase the
cancer risk. Virus induced oncogenic processes are influenced by a complex and unique …

Abstract mAbs have been instrumental for targeted cancer therapies. However, their
relatively large size and physicochemical properties result in a heterogenous distribution in …

Human cytomegalovirus (HCMV) latency and reactivation is regulated by the chromatin
structure at the major immediate early promoter (MIEP) within myeloid cells. Both cellular …