Predicting glycan structure from tandem mass spectrometry via deep learning

J Urban, C Jin, KA Thomsson, NG Karlsson, CM Ives… - Nature …, 2024 - nature.com
Glycans constitute the most complicated post-translational modification, modulating protein
activity in health and disease. However, structural annotation from tandem mass …

O-GlcNAc informatics: advances and trends

C Hou, W Li, Y Li, J Ma - Analytical and Bioanalytical Chemistry, 2024 - Springer
As a post-translational modification, protein glycosylation is critical in health and disease. O-
Linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation), as an …

Systematic Evaluation of Affinity Enrichment Methods for O-GlcNAc Proteomics

C Hou, C Wu, Z Wu, Y Cheng, W Li… - Journal of Proteome …, 2024 - ACS Publications
O-Linked β-N-acetylglucosamine (O-GlcNAc) modification (ie, O-GlcNAcylation) on proteins
plays critical roles in the regulation of diverse biological processes. However, protein O …

Studying the O-GlcNAcome of human placentas using banked tissue samples

S Luna, F Malard, M Pereckas, M Aoki, K Aoki… - …, 2024 - academic.oup.com
O-GlcNAcylation is a dynamic modulator of signaling pathways, equal in magnitude to the
widely studied phosphorylation. With the rapid development of tools for its detection at the …

Integrating HexNAcQuest with glycoproteomics data analysis software to distinguish HexNAc isomers on peptides

C Hou, W Li, Y Li, J Ma - Protein Bioinformatics, 2024 - Springer
Recently, HexNAcQuest was developed to help distinguish peptides modified by HexNAc
isomers, more specifically O-linked β-N-acetylglucosamine (O-GlcNAc) and O-linked α-N …