Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

[HTML][HTML] Soft drusen in age-related macular degeneration: biology and targeting via the oil spill strategies

CA Curcio - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

[HTML][HTML] Measuring the contributions of basal laminar deposit and Bruch's membrane in age-related macular degeneration

AA Sura, L Chen, JD Messinger… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …

Imaging features associated with progression to geographic atrophy in age-related macular degeneration: classification of atrophy meeting report 5

GJ Jaffe, U Chakravarthy, KB Freund, RH Guymer… - Ophthalmology …, 2021 - Elsevier
Purpose To provide an image-based description of retinal features associated with risk for
development of geographic atrophy (GA) in eyes with age-related macular degeneration …

Pachyvitelliform maculopathy: an optical coherence tomography analysis of a novel entity

A Hilely, A Au, WK Lee, MF Levin, D Zur… - British Journal of …, 2024 - bjo.bmj.com
Purpose To describe the optical coherence tomography features of pachyvitelliform
maculopathy (PVM), an acquired vitelliform lesion (AVL) associated with pachychoroid …

[HTML][HTML] Multimodal imaging of nonneovascular age-related macular degeneration

ST Garrity, D Sarraf, KB Freund… - … ophthalmology & visual …, 2018 - tvst.arvojournals.org
Nonneovascular (dry) AMD is a retinal disease with potential for significant central visual
impairment. The hallmarks of this disease are macular drusen, RPE alterations, and …

Adaptive optics ophthalmoscopy: Application to age-related macular degeneration and vascular diseases

M Paques, S Meimon, F Rossant, D Rosenbaum… - Progress in retinal and …, 2018 - Elsevier
Adaptive optics (AO)-enhanced en face retinal imaging, termed here AO ophthalmoscopy
(AOO) has reached a level of robustness which fuels its increasing use in research and …

Visualizing lipid behind the retina in aging and age-related macular degeneration, via indocyanine green angiography (ASHS-LIA)

L Chen, P Yang, CA Curcio - Eye, 2022 - nature.com
Age-related macular degeneration (AMD) causes legal blindness in older adults worldwide.
Soft drusen are the most extensively documented intraocular risk factor for progression to …

Vitelliform maculopathy: diverse etiologies originating from one common pathway

C Iovino, P Ramtohul, A Au, V Romero-Morales… - Survey of …, 2023 - Elsevier
Vitelliform lesions (VLs) are associated with a wide array of macular disorders but are the
result of one common pathway: retinal pigment epithelium (RPE) impairment and phagocytic …

Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina

S Notomi, K Ishihara, NE Efstathiou… - Proceedings of the …, 2019 - National Acad Sciences
The early stages of age-related macular degeneration (AMD) are characterized by the
accumulation of basal laminar deposits (BLamDs). The mechanism for BLamDs …