PARP inhibitors in prostate cancer: clinical applications
H Saeidi, M Sarafbidabad - Molecular Biology Reports, 2024 - Springer
Despite recent advancements in the treatment of metastatic castrate-resistant prostate
cancer (mCRPC), this disease remains lethal. A novel family of targeted pharmaceuticals …
cancer (mCRPC), this disease remains lethal. A novel family of targeted pharmaceuticals …
[HTML][HTML] METTL3 inhibitor suppresses the progression of prostate cancer via IGFBP3/AKT pathway and synergizes with PARP inhibitor
X Chen, M Wang, H Wang, J Yang, X Li… - Biomedicine & …, 2024 - Elsevier
The RNA N 6-methyladenosine (m6A) regulator METTL3 is an important regulatory gene in
various progressive processes of prostate cancer (PCa). METTL3 inhibitors have been …
various progressive processes of prostate cancer (PCa). METTL3 inhibitors have been …
PINK1-Mediated Mitochondrial Activity Confers Olaparib Resistance in Prostate Cancer Cells
Olaparib, a PARP inhibitor, is a targeted therapy used in treating various cancers, including
castration-resistant prostate cancer. Despite its efficacy, resistance to olaparib remains a …
castration-resistant prostate cancer. Despite its efficacy, resistance to olaparib remains a …
Innovations in Metal-Based Nanomedicines to Interfere with the Signaling Communications of Prostate Cancer
Prostate cancer is the second most lethal malignancy in males noticed worldwide. The early
stage symptoms of prostate cancer are often unnoticed, which results in delayed diagnosis …
stage symptoms of prostate cancer are often unnoticed, which results in delayed diagnosis …
Identification of vitamin D-related signature for predicting the clinical outcome and immunotherapy response in hepatocellular carcinoma
T Wang, L Han, J Xu, B Guo - Medicine, 2024 - journals.lww.com
Hepatocellular carcinoma (HCC) is one of the most common cancers globally, seriously
endangering people health. Vitamin D was significantly associated with tumor progression …
endangering people health. Vitamin D was significantly associated with tumor progression …