Background: Antipsychotic-induced metabolic side effects are major concerns in
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …

Schizophrenia is a debilitating psychiatric disorder that is treated with antipsychotics.
However, despite their efficacy, antipsychotics increase the risk of metabolic disorders in a …

Antipsychotic drugs (APDs) are widely prescribed to control various mental disorders. As
mental disorders are chronic diseases, these drugs are often used over a life-time. However …

The present study was conducted to investigate the protective effect of betulin, a triterpene
from the bark of Betula platyphylla Suk, against ethanol-induced alcoholic liver injury and its …

Studies have confirmed that olanzapine, the mainstay treatment for schizophrenia, triggers
metabolic diseases, including non-alcoholic fatty liver disease (NAFLD). However, the …

Aims Chronic treatment with antipsychotics, especially most of atypical ones, leads to
development of metabolic abnormalities. Olanzapine is an atypical antipsychotic widely …

Antipsychotic-induced weight gain (AIWG) is a common side effect of antipsychotic
medication and may contribute to diabetes and coronary heart disease. To expand the …

Abstract Ethnopharmacological relevance The modified Longdan Xiegan Tang (mLXT) has
been used clinically for various neuropsychiatric disorders and liver diseases. The use of …

The antipsychotic drug olanzapine was reported to induce nonalcoholic fatty liver disease
(NAFLD), whereas the underlying mechanism remains incompletely understood. This study …

The aim of this study was to investigate the mechanisms underlying the inhibitory effects of
berberine (BBR) on olanzapine (OLZ)-induced adipogenesis in a well-replicated 3T3-L1 cell …