Ebselen and diphenyl diselenide against fungal pathogens: A systematic review

JL Benelli, VR Poester, LS Munhoz, AM Melo… - Medical …, 2021 - academic.oup.com
Fungal infections are one of the most prevalent diseases in the world and there is a lack of
new antifungal drug development for these diseases. We conducted a systematic review of …

Nano-based formulations as an approach for providing a novel identity for organoselenium compounds

MHM Sari, LM Ferreira, VC Prado, CW Nogueira… - European Journal of …, 2022 - Elsevier
The organoselenium compounds belong to a class of synthetic molecules that displays a
remarkable spectrum of promising pharmacological properties. Despite the huge amount of …

Xanthan gum-based hydrogel containing nanocapsules for cutaneous diphenyl diselenide delivery in melanoma therapy

LM Ferreira, MHM Sari, JH Azambuja… - Investigational New …, 2020 - Springer
The aim of this study was to further evaluate the antitumoral effect of (PhSe) 2-loaded
polymeric nanocapsules (NC (PhSe) 2) against a resistant melanoma cell line (SK-Mel-103) …

[HTML][HTML] Cytoprotective organoselenium compounds for oligodendrocytes

S Shaaban, A Zarrouk, D Vervandier-Fasseur… - Arabian Journal of …, 2021 - Elsevier
Herein we report the synthesis of peptide-like and tetrazole-based organoselenium
compounds via Ugi and Ugi-azide reactions, respectively. The organoselenium compounds' …

Diphenyl diselenide loaded poly (ε-caprolactone) nanocapsules with selective antimelanoma activity: Development and cytotoxic evaluation

LM Ferreira, VF Cervi, MHM Sari, AV Barbieri… - Materials Science and …, 2018 - Elsevier
Malignant cutaneous melanoma is a result of the melanocytes disordered proliferation in the
epidermis and is considered the most severe skin cancer because of its high metastatic rate …

Locust bean gum nano-based hydrogel for vaginal delivery of diphenyl diselenide in the treatment of trichomoniasis: formulation characterization and in vitro …

FP Reis, GV Rigo, CW Nogueira, T Tasca, MHM Sari… - Pharmaceutics, 2022 - mdpi.com
Trichomoniasis is the most common nonviral sexually transmitted infection in the world, but
its available therapies present low efficacy and high toxicity. Diphenyl diselenide (PhSe2) is …

Antitumor action of diphenyl diselenide nanocapsules: in vitro assessments and preclinical evidence in an animal model of glioblastoma multiforme

LM Ferreira, JH Azambuja, EF da Silveira… - Journal of Trace …, 2019 - Elsevier
Background Gliomas are the most aggressive malignant tumors of the central nervous
system. The diphenyl diselenide [(PhSe) 2] is an organoselenium compound that has …

p, p′-Methoxyl-diphenyl diselenide-loaded polymeric nanocapsules are chemically stable and do not induce toxicity in mice

MHM Sari, LM Ferreira, VA Zborowski… - European Journal of …, 2017 - Elsevier
Organoselenium compounds have been targeted to new therapeutic tools development due
to their pharmacological actions. However, some toxicity issues and physicochemical …

Diphenyl diselenide‐loaded nanocapsules in silver catfish feed enhance growth, improve muscle antioxidant/oxidant status and increase selenium deposition …

MD Baldissera, CF Souza, KO Alessio… - Aquaculture …, 2020 - Wiley Online Library
The aim of this study was to determine whether feed supplementation with
nanoencapsulated Ph2Se2 would improve the growth performance of silver catfish and …

p, p'-Methoxyl-diphenyl diselenideincorporation into polymeric nanocapsules improves its antinociceptive action: Physicochemical and behavioral studies

MHM Sari, LM Ferreira, V AngonesiZborowski… - Colloids and Surfaces B …, 2017 - Elsevier
Abstract The p, p'-methoxyl-diphenyl diselenide [(OMePhSe) 2] is an, organoselenium
compound that elicits antinociceptive action in different, animal models of pain. However, the …