The mechanisms of perineuronal net abnormalities in contributing aging and neurological diseases

Y Dong, K Zhao, X Qin, G Du, L Gao - Ageing Research Reviews, 2023 - Elsevier
The perineuronal net (PNN) is a highly latticed extracellular matrix in the central nervous
system, which is composed of hyaluronic acid, proteoglycan, hyaluronan and proteoglycan …

Optogenetics Neuromodulation of the Nose

F Xiang, S Zhang, M Tang, P Li, H Zhang… - Behavioural …, 2024 - Wiley Online Library
Recently developed optogenetic technology, which allows high‐fidelity control of neuronal
activity, has been applied to investigate the neural circuits underlying sensory processing …

Genetic labeling reveals spatial and cellular expression pattern of neuregulin 1 in mouse brain

CY Ding, YT Ding, H Ji, YY Wang, X Zhang, DM Yin - Cell & Bioscience, 2023 - Springer
Background Where the gene is expressed determines the function of the gene. Neuregulin 1
(Nrg1) encodes a tropic factor and is genetically linked with several neuropsychiatry …

ErbB4 deficiency exacerbates olfactory dysfunction in an early-stage Alzheimer's disease mouse model

X Deng, X Liu, Y Wei, K Wang, J Zhu, J Zhong… - Acta Pharmacologica …, 2024 - nature.com
Olfactory dysfunction is increasingly recognized as an early indicator of Alzheimer's disease
(AD). Aberrations in GABAergic function and the excitatory/inhibitory (E/I) balance within the …