Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …

Brain circuits undergo substantial structural changes during development, driven by the
formation, stabilization, and elimination of synapses. Synaptic connections continue to …

Cortical state, defined by population-level neuronal activity patterns, determines sensory
perception. While arousal-associated neuromodulators—including norepinephrine (NE) …

Astrocytes negatively impact neuronal development in many models of neurodevelopmental
disorders (NDs); however, how they do this, and if mechanisms are shared across disorders …

Astrocytes control the formation of specific synaptic circuits via cell adhesion and secreted
molecules. Astrocyte synaptogenic functions are dependent on the establishment of their …

Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …

Reactive astrocytes play a pivotal role in the pathogenesis of neurological diseases;
however, their functional phenotype and the downstream molecules by which they modify …

Astrocytes play crucial roles in regulating brain circuit formation and physiology. Recent
technological advances have revealed unprecedented levels of astrocyte diversity …

Astrocytes play an integral role in the development, maturation, and refinement of neuronal
circuits. Astrocytes secrete proteins and lipids that instruct the formation of new synapses …

Astrocytes are ubiquitous within the central nervous system (CNS). These cells possess
many individual processes which extend out into the neuropil, where they interact with a …