Hematopoietic stem cells: an overview

YM Mosaad - Transfusion and Apheresis Science, 2014 - Elsevier
Considerable efforts have been made in recent years in understanding the mechanisms that
govern hematopoietic stem cell (HSC) origin, development, differentiation, self-renewal …

A review of the mutagenic potential of N‐ethyl‐N‐nitrosourea (ENU) to induce hematological malignancies

P Nath, D Maiti - Journal of Biochemical and Molecular …, 2022 - Wiley Online Library
This review is intended to summarize the existing literature on the mutagenicity of N‐ethyl‐N‐
nitrosourea (ENU) in inducing hematological malignancies, including acute myeloid …

Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis

Z Chen, D Huo, L Li, Z Liu, Z Li, S Xu… - Journal of Experimental …, 2021 - rupress.org
The oncogene DEK is found fused with the NUP214 gene creating oncoprotein DEK-
NUP214 that induces acute myeloid leukemia (AML) in patients, and secreted DEK protein …

Pharmacologically active microcarriers influence VEGF‐A effects on mesenchymal stem cell survival

C Penna, MG Perrelli, JP Karam… - Journal of Cellular …, 2013 - Wiley Online Library
Resistance of transplanted mesenchymal stem cells (MSC s) in post‐ischemic heart is
limited by their poor vitality. Vascular‐endothelial‐growth‐factor‐A (VEGF‐A) as such or …

The effect of melatonin on Hippo signaling pathway in dental pulp stem cells

E Baysal, EB Zırh, E Buber, TK Jakobsen… - Neurochemistry …, 2021 - Elsevier
Dental pulp stem cells (DPSCs) have a high capacity to differentiate into the neuronal cell
lineage. Meanwhile, both Hippo signaling and melatonin are key regulators in neuronal …

[HTML][HTML] Mesenchymal stem cells as a feeder layer can prevent apoptosis of expanded hematopoietic stem cells derived from cord blood

R Mehrasa, H Vaziri, A Oodi, M Khorshidfar… - … journal of molecular …, 2014 - ncbi.nlm.nih.gov
Umbilical cord blood (UCB) has been used for transplantation in the treatment of
hematologic disorders as a source of hematopoietic stem cells (HSCs). Because of …

A mathematical model of the transition from normal hematopoiesis to the chronic and accelerated-acute stages in myeloid leukemia

LG Parajdi, R Precup, EA Bonci, C Tomuleasa - Mathematics, 2020 - mdpi.com
A mathematical model given by a two-dimensional differential system is introduced in order
to understand the transition process from the normal hematopoiesis to the chronic and …

Expansion of Cord Blood CD34+ Cells in Presence of zVADfmk and zLLYfmk Improved Their In Vitro Functionality and In Vivo Engraftment in NOD/SCID Mouse.

VM Sangeetha, VP Kale, LS Limaye - PloS one, 2010 - search.ebscohost.com
Background: Cord blood (CB) is a promising source for hematopoietic stem cell
transplantations. The limitation of cell dose associated with this source has prompted the ex …

Tauroursodeoxycholic acid increases neural stem cell pool and neuronal conversion by regulating mitochondria-cell cycle retrograde signaling

JM Xavier, AL Morgado, CMP Rodrigues, S Solá - Cell Cycle, 2014 - Taylor & Francis
The low survival and differentiation rates of stem cells after either transplantation or neural
injury have been a major concern of stem cell-based therapy. Thus, further understanding …

Effect of EGF and FGF on the expansion properties of human umbilical cord mesenchymal cells

P Salehinejad, NB Alitheen, A Mandegary… - In Vitro Cellular & …, 2013 - Springer
Mesenchymal stem cells have been increasingly introduced to have great potential in
regenerative medicine, immunotherapy, and gene therapy due to their unique properties of …