Burn injuries are under-appreciated injuries that are associated with substantial morbidity
and mortality. Burn injuries, particularly severe burns, are accompanied by an immune and …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. Sepsis can induce acute kidney injury and multiple organ failures …

The production of neutrophil extracellular traps (NETs) is a process that enables neutrophils
to help catch and kill bacteria. However, increasing evidence suggests that this process …

Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Thrombotic complications are still a major health risk worldwide. Our view on the
pathophysiology of thrombosis has significantly changed since the discovery of neutrophil …

Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells characterized by
their immunosuppressive functions. MDSCs expand during chronic and acute inflammatory …

Emerged evidence has indicated that immunosuppression is involved in the occurrence and
development of sepsis. To provide clinical practice recommendations on the immune …

Burn is an under-appreciated trauma that is associated with unacceptably high morbidity
and mortality. Although the survival rate after devastating burn injuries has continued to …