Inhalation delivery of nucleic acid gene therapies in preclinical drug development
CA Ruzycki, D Montoya, H Irshad, J Cox… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Inhaled gene therapy programs targeting diseases of the lung have seen
increasing interest in recent years, though as of yet no product has successfully entered the …
increasing interest in recent years, though as of yet no product has successfully entered the …
Recent Developments in Aerosol Pulmonary Drug Delivery: New Technologies, New Cargos, and New Targets
IR Woodward, CA Fromen - Annual Review of Biomedical …, 2024 - annualreviews.org
There is nothing like a global pandemic to motivate the need for improved respiratory
treatments and mucosal vaccines. Stimulated by the COVID-19 pandemic, pulmonary …
treatments and mucosal vaccines. Stimulated by the COVID-19 pandemic, pulmonary …
New air-jet dry powder insufflator for high-efficiency aerosol delivery to rats
Pulmonary deposition of lung-targeted therapeutic aerosols can achieve direct drug delivery
to the site of action, thereby enhancing the efficacy and reducing systemic exposure. In this …
to the site of action, thereby enhancing the efficacy and reducing systemic exposure. In this …
Inhalable tobramycin EEG powder formulation for treating Pseudomonas aeruginosa-induced lung infection
Pulmonary delivery of antibiotics is an effective strategy in treating bacterial lung infection for
cystic fibrosis patients, by achieving high local drug concentrations and reducing overall …
cystic fibrosis patients, by achieving high local drug concentrations and reducing overall …
Characterization of pediatric extrathoracic aerosol deposition with air-jet dry powder inhalers
The use of air-jet dry powder inhalers (DPIs) offers a number of advantages for the
administration of pharmaceutical aerosols, including the ability to achieve highly efficient …
administration of pharmaceutical aerosols, including the ability to achieve highly efficient …
Prediction of Transport and Deposition of Porous Particles in the Respiratory System Using Eulerian–Lagrangian Approach
S Eshaghi, H Khaleghi… - International Journal for …, 2024 - Wiley Online Library
Deep lung delivery is crucial for respiratory disease treatment. Although nano and
submicron particles exhibited a good deposition efficiency in deep regions of the lung …
submicron particles exhibited a good deposition efficiency in deep regions of the lung …
Advances in Pulmonary Drug Delivery Systems and Inhalation Formulations
Inhalation therapy has been popular for treatment of pulmonary diseases such as asthma
and chronic obstructive pulmonary diseases (COPD). Recently, inhalation therapy has also …
and chronic obstructive pulmonary diseases (COPD). Recently, inhalation therapy has also …