Chondroitin Sulfate (CS) is an anionic hetero polysaccharide possessing anti-inflammatory,
antioxidant, antitumor, anticoagulant and antithrombogenic activities. It is biodegradable and …

Chondroitin sulfate (CS), a natural anionic mucopolysaccharide, belonging to the
glycosaminoglycan family, acts as the primary element of the extracellular matrix (ECM) of …

The requirement for the favorable therapeutics against ulcerative colitis (UC) is that anti-
inflammatory drugs can be specifically internalized by macrophages and subsequently be …

CRISPR-Cas9 has emerged as a versatile genome-editing platform. However, due to the
large size of the commonly used CRISPR-Cas9 system, its effective delivery has been a …

Tumor-associated macrophages (TAMs) are abundant in the tumor microenvironment and
promote the tumor progression via multiple mechanisms. CD47 is overexpressed in most …

Liver fibrosis is a serious liver disease associated with high morbidity and mortality. The
activation of hepatic stellate cells (HSCs) and the overproduction of extracellular matrix …

Polymeric vectors have shown great promise in the development of safe and efficient gene
delivery systems; however, only a few have been developed in clinical settings due to poor …

The extremely low efficient cytosolic release of the internalized siRNA has emerged recently
as a central issue for siRNA delivery, while there is a lack of guidelines to facilitate the …

Programmable drug delivery systems hold great promise to enhance cancer treatment.
Herein, a programmable drug delivery system using a chondroitin sulfate (CS)-based …

Hyaluronic acid (HA) and chondroitin sulfate (CS) polymers are extensively used for various
biomedical applications, such as for tissue engineering, drug delivery, and gene delivery …