Biomimetic materials have emerged as attractive and competitive alternatives for tissue
engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or …

Background R. suavissimus (Rubus suavissimus S. Lee), also known as Chinese sweet tea,
is a deciduous shrub of the genus Rubus in the family Rosaceae in China. R. suavissimus …

Hyaluronic acid is a glycosaminoglycan biopolymer widely present throughout connective
and epithelial tissue, and has been of great interest for medical and cosmetic applications. In …

Rubusoside (Rub) is a highly sweet diterpene glycoside mainly isolated from the leaves of
Rubus suavissimus (Rosaceae). It has been used as a low-calorie natural sweetener for …

Dental caries is a biofilm-mediated disease in which Streptococcus mutans is the main
pathogenic microorganism, and its incidence is closely related to sucrose. Rubusoside is a …

As a natural sweetening and solubilizing agent, rubusoside has great potential in the
application of healthy beverages and pharmaceuticals. However, the direct extraction and …

The oral bioavailability of poorly soluble drugs has always been the focus of pharmaceutical
researchers. We innovatively combined nanocrystal technology and solid dispersion …

Helicobacter pylori infection is commonly treated with a combination of antibiotics and
proton pump inhibitors. However, since H. pylori is becoming increasingly resistant to …

Terpenoids are important secondary metabolites in Rubus. Rubusoside is a relatively
specific diterpenoid bioactive component in the leaves of Chinese Sweet Tea (Rubus …

Monoglucosylation of rubusoside not only could increase its structural diversity but may also
improve its taste. To biosynthesize the monoglucosyl rubusosides, a series of …