Erdheim–Chester disease (ECD) is a rare form of non-Langerhans-cell histiocytosis,
associated in more than 50% of cases to BRAF V600E mutations in early multipotent …

Mitogen-activated protein kinases (MAPKs) are a family of ubiquitous eukaryotic signal
transduction enzymes which link extracellular stimuli to intracellular gene expression …

Objective: Present study focused on the influence of lncRNA MALAT1 on coronary
atherosclerotic heart disease (CAD) by regulating miR-15b-5p/MAPK1 and mTOR signaling …

Background Intertumoral heterogeneity represents a significant hurdle to identifying
optimized targeted therapies in gastric cancer (GC). To realize precision medicine for GC …

Background Primary systemic treatment for ovarian cancer is surgery, followed by platinum
based chemotherapy. Platinum resistant cancers progress/recur in approximately 25% of …

Copy-number alterations (CNAs) are a hallmark of cancer and can regulate cancer cell
states via altered gene expression values. Herein, we have developed a copy-number …

Signaling networks are key regulators of cellular function. Although the concentrations of
signaling proteins are perturbed in disease states, such as cancer, and are modulated by …

Wang J, Xiao T, Zhao M. Onco Targets Ther. 2019; 12: 7307–7321. The Editor and Publisher
of OncoTargets and Therapy wish to retract the published article. Concerns were raised over …

Ovarian cancer is the major cause of gynecologic cancer‐related mortality. Regardless of
outstanding advances, which have been made for improving the prognosis, diagnosis, and …

Ovarian cancer (OC) is the sixth most common cancer in women worldwide. Despite
advances in detection and therapies, it still represents the most lethal gynecologic …