[HTML][HTML] Aberrant LncRNA expression in leukemia

J Gao, F Wang, P Wu, Y Chen, Y Jia - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Leukemia is a common malignant cancer of the hematopoietic system, whose pathogenesis
has not been fully elucidated. Long noncoding RNAs (lncRNAs) are transcripts longer than …

Long non-coding RNA and acute leukemia

GM Cruz-Miranda, A Hidalgo-Miranda… - International journal of …, 2019 - mdpi.com
Acute leukemia (AL) is the main type of cancer in children worldwide. Mortality by this
disease is high in developing countries and its etiology remains unanswered. Evidences …

Retracted: Knockdown of long non‐coding RNA MALAT1 inhibits growth and motility of human hepatoma cells via modulation of miR‐195

D Liu, Y Zhu, J Pang, X Weng, X Feng, Y Guo - 2018 - Wiley Online Library
The metastasis‐associated lung adenocarcinoma transcription 1 (Malat1) is a long non‐
coding RNA (lncRNA), exerts oncogenic role in multiple cancers, including hepatocellular …

Diagnostic and therapeutic implications of long non-coding rnas in leukemia

V Gasic, T Karan-Djurasevic, D Pavlovic, B Zukic… - Life, 2022 - mdpi.com
Simple Summary Research on leukemia has often led to novel approaches in clinical
practice. Cytogenetical and molecular markers have been introduced in treatment protocols …

Long non-coding RNA signatures in Lymphopoiesis and lymphoid malignancies

H Baghdadi, R Heidari, M Zavvar, N Ahmadi… - Non-coding RNA, 2023 - mdpi.com
Lymphoid cells play a critical role in the immune system, which includes three subgroups of
T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in …

[HTML][HTML] Advances in biology of acute lymphoblastic leukemia (ALL) and therapeutic implications

M Mohseni, H Uludag, JM Brandwein - American journal of blood …, 2018 - ncbi.nlm.nih.gov
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer and also occurs in
adults. Although the outcomes of multi-agent chemotherapy regimens have greatly …

Linear and circular long non-coding RNAs in acute lymphoblastic leukemia: from pathogenesis to classification and treatment

Y Maimaitiyiming, L Ye, T Yang, W Yu… - International Journal of …, 2022 - mdpi.com
The coding regions account for only a small part of the human genome, and the remaining
vast majority of the regions generate large amounts of non-coding RNAs. Although non …

Drug resistance biomarkers and their clinical applications in childhood acute lymphoblastic leukemia

N Aberuyi, S Rahgozar, ES Ghodousi… - Frontiers in oncology, 2020 - frontiersin.org
Biomarkers are biological molecules found in body fluids or tissues, which can be
considered as indications of a normal or abnormal process, or of a condition or disease …

Non-coding RNAs in leukemia drug resistance: new perspectives on molecular mechanisms and signaling pathways

A Rahmati, A Mafi, O Vakili, F Soleymani, Z Alishahi… - Annals of …, 2024 - Springer
Like almost all cancer types, timely diagnosis is needed for leukemias to be effectively
cured. Drug efflux, attenuated drug uptake, altered drug metabolism, and epigenetic …

Inflammation and tissue homeostasis: The NF-κB system in physiology and malignant progression

GI Lambrou, K Hatziagapiou, S Vlahopoulos - Molecular Biology Reports, 2020 - Springer
Disruption of tissue function activates cellular stress which triggers a number of mechanisms
that protect the tissue from further damage. These mechanisms involve a number of …