Recent gene expression profiling of breast cancer has identified specific subtypes with
clinical, biologic, and therapeutic implications. The basal-like group of tumors is …

Squamous cell carcinoma of the head and neck (HNSCC) is a relatively common human
cancer characterized by high morbidity, high mortality, and few therapeutic options outside …

Trophoblast cells play an essential role in the interactions between the fetus and mother.
Mouse trophoblast stem (TS) cells have been derived and used as the best in vitro model for …

Following implantation, the human embryo undergoes major morphogenetic transformations
that establish the future body plan. While the molecular events underpinning this process …

Over the past decades, consistent studies have shown that race/ethnicity have a great
impact on cancer incidence, survival, drug response, molecular pathways and epigenetics …

Epithelial-to-mesenchymal transition (EMT) is a process that plays essential roles in
development and wound healing that is characterized by loss of homotypic adhesion and …

The availability of targeted therapies has created a need for precise subtyping of non-small
cell lung carcinomas (NSCLCs). The aim of this study was to assess the utility of …

The severe acute respiratory syndrome (SARS) pandemic in Toronto resulted in a large
number of autopsies on its victims. We describe the pulmonary pathology of patients who …

Purpose Recent advances in treatment of lung cancer require greater accuracy in the
subclassification of non–small-cell lung cancer (NSCLC). Targeted therapies which inhibit …

Abstract Introduction Cytokeratin (CK) 14, one of several markers expressed in normal
myoepithelial/basal cells, is also expressed in a proportion of breast carcinomas. Previous …