Background: New-generation antidepressants (NGAs) are the latest additions to the
clinician's arsenal in the fight against depression. After the introduction of selective serotonin …

In this paper, the binding of trazodone hydrochloride (TZH) to bovine serum albumin (BSA)
was investigated by spectroscopic (fluorescence, spectrophotometry and circular dichroism) …

In recent years, analytical chemistry has been facing new challenges, particularly in
developing low-cost, green, and easy-to-reproduce methods. In this work, a simple …

Inclusion complex of trazodone hydrochloride (TRD) with hydroxypropyl-β-cyclodextrin (HP-
βCD) has been investigated by 1H NMR, 13CNMR, 2D NMR, FTIR and UV/visible …

Two sensitive and simple spectrophotometric methods are developed for the determination
of trazodone HCl, famotidine, and diltiazem HCl in pure and pharmaceutical preparations …

Background Given the importance of achieving optimal therapeutical concentration in
patients treated with antidepressants, this study investigates a novel technique for the …

Purpose. The purpose of this study was to establish an automated approach to salt selection
and to search for unique trazodone salts for new applications. Methods. Automated …

A simple and reliable liquid chromatographic procedure is described for the determination of
trazodone in pharmaceutical formulations and urine samples. The optimized procedure uses …

This study improved three potentiometric sensors for measuring the drug trazodone
hydrochloride. The constructive sensors were designed for the preparation of electro-active …

A sensitive spectrofluorimetric method was developed to determine trazodone hydrochloride
in its formulation and urine sample. The principle of the developed method is based on the …