The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings

AV Skalny, M Aschner, EV Silina, VA Stupin… - Biomolecules, 2023 - mdpi.com
The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …

Disparities in osteoporosis prevention and care: understanding gender, racial, and ethnic dynamics

N Onizuka, T Onizuka - Current Reviews in Musculoskeletal Medicine, 2024 - Springer
Purpose Osteoporosis, the most prevalent metabolic bone disease, significantly impacts
global public health by increasing fracture risks, particularly among post-menopausal …

Fragility Score: a REMS-based indicator for the prediction of incident fragility fractures at 5 years

P Pisani, F Conversano, M Muratore, G Adami… - Aging Clinical and …, 2023 - Springer
Background Accurate estimation of the imminent fragility fracture risk currently represents a
challenging task. The novel Fragility Score (FS) parameter, obtained during a …

[HTML][HTML] The Importance of Vitamin K and the Combination of Vitamins K and D for Calcium Metabolism and Bone Health: A Review

JO Aaseth, TE Finnes, M Askim, J Alexander - Nutrients, 2024 - mdpi.com
The aim of the present review is to discuss the roles of vitamin K (phylloquinone or
menaquinones) and vitamin K-dependent proteins, and the combined action of the vitamins …

[HTML][HTML] Standard in vitro evaluations of engineered bone substitutes are not sufficient to predict in vivo preclinical model outcomes

LP Hatt, AR Armiento, K Mys, K Thompson… - Acta Biomaterialia, 2023 - Elsevier
Understanding the optimal conditions required for bone healing can have a substantial
impact to target the problem of non–unions and large bone defects. The combination of …

[HTML][HTML] Exploring the Role of Hormones and Cytokines in Osteoporosis Development

E Umur, SB Bulut, P Yiğit, E Bayrak, Y Arkan, F Arslan… - Biomedicines, 2024 - mdpi.com
The disease of osteoporosis is characterized by impaired bone structure and an increased
risk of fractures. There is a significant impact of cytokines and hormones on bone …

[HTML][HTML] Osteoporosis: Spotlight on current approaches to pharmacological treatment

D Sindel - Turkish journal of physical medicine and rehabilitation, 2023 - ncbi.nlm.nih.gov
Despite the availability of safe and effective anti-osteoporosis treatments, osteoporosis
continues to be undertreated. The increase in fragility fractures, which is the main clinical …

Tricrilactones A–H, Potent Antiosteoporosis Macrolides with Distinctive Ring Skeletons from Trichocladium crispatum, an Alpine Moss‐Associated Fungus

WB Han, YJ Zhai, R Zhang, XS Gong, JQ Li… - Angewandte …, 2023 - Wiley Online Library
Abstract Tricrilactones A–H (1–8), a new family of oligomeric 10‐membered macrolides
featuring collectively five unique ring skeletons, were isolated from a hitherto unexplored …

[HTML][HTML] Moringa oleifera leaf extract induces osteogenic-like differentiation of human osteosarcoma SaOS2 cells

MI Khan, S Siddiqui, MA Barkat, FS Alhodieb… - Journal of Traditional …, 2022 - Elsevier
Introduction Moringa oleifera is known as a 'natural nutrition of the tropics' because it
provides vital nutritional supplements and a variety of pharmacological benefits. The focus of …

Romosozumab in patients who experienced an on-study fracture: post hoc analyses of the FRAME and ARCH phase 3 trials

J Lane, B Langdahl, M Stone, A Kurth, M Oates… - Osteoporosis …, 2024 - Springer
Post hoc analysis of FRAME and ARCH revealed that on-study nonvertebral and vertebral
fractures by Month 12 were less common in women initially treated with romosozumab …