GABA has attracted great attention over the last several decades due to its ubiquity in life. It
is an important molecule naturally present in considerable amounts in many feed and food …

Compared with traditional sampling methods, microdialysis is a technique for protein
unbound drug sampling without withdrawal of biological fluids and involving minimal …

Serotonin synthesis in mammals is initiated by 2 distinct tryptophan hydroxylases (TPH),
TPH1 and TPH2. By genetically ablating TPH2, we created mice (Tph2−/−) that lack …

Prenatal viral infection has been associated with development of schizophrenia and autism.
Our laboratory has previously shown that viral infection causes deleterious effects on brain …

Maternal infection during pregnancy enhances the offspring's risk for severe
neuropsychiatric disorders in later life, including schizophrenia. Recent attempts to model …

To better understand the biology of tameness, ie tolerance of human presence and
handling, we analyzed two lines of wild-derived rats (Rattus norvegicus) artificially selected …

Recent evidence indicates that glutamate homeostasis and neurotransmission are altered in
major depressive disorder, but the nature of the disruption and the mechanisms by which it …

In this work, a simple and convenient sensory platform based on the fluorescence
quenching and paper-based probe has been developed using carbon dots (CQDs). The …

BACKGROUND: Poststroke emotional and behavioral abnormalities have an impact on
outcome but have scarcely been characterized in animal models. We tested whether brief …

A simple and sensitive method for the separation and quantitation of glutamine, glutamate,
pyroglutamate, and γ-aminobutyric acid (GABA) in cerebrospinal fluid (CSF) is presented …