A covalently modified hydrogel blend of hyaluronan–methyl cellulose with peptides and growth factors influences neural stem/progenitor cell fate
With the goal of controlling stem cell fate, for ultimate application in cell delivery, we
synthesized a cell delivery vehicle comprised of an injectable hydrogel of hyaluronan (HA) …
synthesized a cell delivery vehicle comprised of an injectable hydrogel of hyaluronan (HA) …
Organophosphorus pesticides promote protein cross-linking
LM Schopfer, S Onder, O Lockridge - Chemical Research in …, 2022 - ACS Publications
Exposure to organophosphorus pesticides (OP) can have chronic adverse effects that are
independent of inhibition of acetylcholinesterase, the classic target for acute OP toxicity. In …
independent of inhibition of acetylcholinesterase, the classic target for acute OP toxicity. In …
Molecular hybridization combining tumor homing and penetrating peptide domains for cellular targeting
R Goyal, G Jerath, A Chandrasekharan… - Drug delivery and …, 2022 - Springer
A complete peptide-based drug delivery unit has been designed with a tumor homing
domain chemically linked to a syndiotactic cell-penetrating domain. The designed peptides …
domain chemically linked to a syndiotactic cell-penetrating domain. The designed peptides …
Development of nanomaterial enabling highly sensitive surface‐assisted laser desorption/ionization mass spectrometry peptide analysis
Rationale Surface‐assisted laser desorption/ionization mass spectrometry (SALDI‐MS) is an
approach derived from matrix‐assisted laser desorption/ionization (MALDI)‐MS which …
approach derived from matrix‐assisted laser desorption/ionization (MALDI)‐MS which …
Laser desorption ionization mass spectrometry of protein tryptic digests on nanostructured silicon plates
We report on the simple application of a new nanostructured silicon (NanoSi) substrate as
laser desorption/ionization (LDI)-promoting surface for high-throughput identification of …
laser desorption/ionization (LDI)-promoting surface for high-throughput identification of …
Quantitating α-amidated peptide degradation by separative technologies and ultra-high resolution mass spectrometry
Abstract α-amidation of peptides is a C-terminal modification allowing to improve half-life of
therapeutic peptides. However, due to storage conditions, this C-terminal amide function can …
therapeutic peptides. However, due to storage conditions, this C-terminal amide function can …
Silica nanoparticles pre-spotted onto target plate for laser desorption/ionization mass spectrometry analyses of peptides
We report on the simple deposition of Stöber silica nanoparticles (SiO2 NPs) on
conventional MALDI target plate for high throughput laser desorption/ionization mass …
conventional MALDI target plate for high throughput laser desorption/ionization mass …
Dissociation Pattern of Sodiated Amide Peptides as a Tool for De Novo Sequencing
E Logerot, C Enjalbal - Journal of the American Society for Mass …, 2020 - ACS Publications
As part of the de novo sequencing issue, new approaches have to be found to sequence
small natural peptides (< 15–20 residues), which often present amino acid compositions …
small natural peptides (< 15–20 residues), which often present amino acid compositions …
[HTML][HTML] Dichlorvos-induced formation of isopeptide crosslinks between proteins in SH-SY5Y cells
LM Schopfer, O Lockridge - Analytical biochemistry, 2022 - Elsevier
Chlorpyrifos oxon catalyzes the crosslinking of proteins via an isopeptide bond between
lysine and glutamic acid or aspartic acid in studies with purified proteins. Our goal was to …
lysine and glutamic acid or aspartic acid in studies with purified proteins. Our goal was to …
Tandem mass spectrometry for structural characterization of doubly-charged N-linked glycopeptides
HTK Wong, X Chen, S Zhang, TY Lui… - Journal of the …, 2022 - ACS Publications
Three dissociation methods, including collision-induced dissociation (CID), electron capture
dissociation (ECD), and electronic excitation dissociation (EED), were systematically …
dissociation (ECD), and electronic excitation dissociation (EED), were systematically …