The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2019)

S Umemura, H Arima, S Arima, K Asayama… - Hypertension …, 2019 - nature.com
The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Arterial hypertension

S Brouwers, I Sudano, Y Kokubo, EM Sulaica - The Lancet, 2021 - thelancet.com
Arterial hypertension is the most important contributor to the global burden of disease;
however, disease control remains poor. Although the diagnosis of hypertension is still based …

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled …

M Azizi, K Sanghvi, M Saxena, P Gosse, JP Reilly… - The Lancet, 2021 - thelancet.com
Background Endovascular renal denervation reduces blood pressure in patients with mild-to-
moderate hypertension, but its efficacy in patients with true resistant hypertension has not …

Resistant hypertension: detection, evaluation, and management: a scientific statement from the American Heart Association

RM Carey, DA Calhoun, GL Bakris, RD Brook… - …, 2018 - Am Heart Assoc
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a
patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a …

Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial

M Azizi, RE Schmieder, F Mahfoud, MA Weber… - The Lancet, 2018 - thelancet.com
Background Early studies suggest that radiofrequency-based renal denervation reduces
blood pressure in patients with moderate hypertension. We investigated whether an …

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of …

DE Kandzari, M Böhm, F Mahfoud, RR Townsend… - The Lancet, 2018 - thelancet.com
Background Previous catheter-based renal denervation studies have reported variable
efficacy results. We aimed to evaluate safety and blood pressure response after renal …

Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised …

RR Townsend, F Mahfoud, DE Kandzari, K Kario… - The Lancet, 2017 - thelancet.com
Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …

Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal …

M Czesnikiewicz-Guzik, G Osmenda… - European heart …, 2019 - academic.oup.com
Aims Inflammation is an important driver of hypertension. Periodontitis is a chronic
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …

A controlled trial of renal denervation for resistant hypertension

DL Bhatt, DE Kandzari, WW O'Neill… - … England Journal of …, 2014 - Mass Medical Soc
Background Prior unblinded studies have suggested that catheter-based renal-artery
denervation reduces blood pressure in patients with resistant hypertension. Methods We …

Effects of lifestyle modification on patients with resistant hypertension: results of the TRIUMPH randomized clinical trial

JA Blumenthal, AL Hinderliter, PJ Smith, S Mabe… - Circulation, 2021 - Am Heart Assoc
Background: Although lifestyle modifications generally are effective in lowering blood
pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or …