The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Arterial hypertension is the most important contributor to the global burden of disease;
however, disease control remains poor. Although the diagnosis of hypertension is still based …

Background Endovascular renal denervation reduces blood pressure in patients with mild-to-
moderate hypertension, but its efficacy in patients with true resistant hypertension has not …

Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a
patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a …

Background Early studies suggest that radiofrequency-based renal denervation reduces
blood pressure in patients with moderate hypertension. We investigated whether an …

Background Previous catheter-based renal denervation studies have reported variable
efficacy results. We aimed to evaluate safety and blood pressure response after renal …

Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …

Aims Inflammation is an important driver of hypertension. Periodontitis is a chronic
inflammatory disease, which could provide a mechanism for pro-hypertensive immune …

Background: Although lifestyle modifications generally are effective in lowering blood
pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or …

Background Prior unblinded studies have suggested that catheter-based renal-artery
denervation reduces blood pressure in patients with resistant hypertension. Methods We …