Advances in metagenomics have allowed a detailed study of the gut microbiome, and its
role in human health and disease. Infants born prematurely possess a fragile gut microbial …

Consumption of probiotics as a useful functional food improves the host's wellbeing, and,
when paired with prebiotics (indigestible dietary fibre/carbohydrate), often benefits the host …

The significance of Bifidobacterium to human health can be appreciated from its early
colonization of the neonatal gut, where Bifidobacterium longum represents the most …

Preterm birth is a major contributor to neonatal morbidity and mortality. Complications of
prematurity such as bronchopulmonary dysplasia (BPD, affecting the lung), pulmonary …

A key aspect of postnatal intestinal adaptation is the establishment of symbiotic relationships
with co-evolved gut microbiota. Necrotizing enterocolitis (NEC) is the most severe disease …

Background & Aims Single immunoglobulin interleukin-1–related receptor (SIGIRR) is a
major inhibitor of Toll-like receptor signaling. Our laboratory identified a novel SIGIRR stop …

Background Human health is seriously threatened by antibiotic-induced intestinal disorders.
Herein, we aimed to determine the effects of Autoinducer-2 (AI-2) combined with …

Necrotizing enterocolitis (NEC) represents one of the major causes of morbidity and
mortality in premature infants. Several recent studies, however, have contributed to a better …

Single immunoglobulin interleukin-1-related receptor (SIGIRR), toll-interacting protein
(TOLLIP), and A20 are major inhibitors of toll-like receptor (TLR) signaling induced …

Postnatal acquisition of the microbiome is critical to infant health. In preterm infants, empiric
use of antibiotics is common, with significant health consequences. To understand the …