In recent decades, obesity has extensively emerged to the level of pandemics. It's significantly associated with serious co-morbidities that could decrease life quality and even …
P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and, therefore, biological processes in different tissues. A major function of miRNAs in adipose …
Metabolic disorders are characterized by the inability to properly use and/or store energy. The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through …
E Arner, N Mejhert, A Kulyté, PJ Balwierz… - Diabetes, 2012 - Am Diabetes Assoc
In obesity, white adipose tissue (WAT) inflammation is linked to insulin resistance. Increased adipocyte chemokine (CC motif) ligand 2 (CCL2) secretion may initiate adipose …
R A. McGregor, M S. Choi - Current molecular medicine, 2011 - benthamdirect.com
Worldwide obesity is a growing health problem, associated with increased risk of chronic disease. Understanding the molecular basis of adipogenesis and fat cell development in …
LE Zaragosi, B Wdziekonski, KL Brigand, P Villageois… - Genome biology, 2011 - Springer
Background In severe obesity, as well as in normal development, the growth of adipose tissue is the result of an increase in adipocyte size and numbers, which is underlain by the …
A Meerson, M Traurig, V Ossowski, JM Fleming… - Diabetologia, 2013 - Springer
Aims/hypothesis MicroRNAs (miRNAs) are short endogenous RNAs that regulate multiple biological processes including adipogenesis and fat metabolism. We sought to identify …
Obesity is a metabolic condition usually accompanied by insulin resistance (IR), type 2 diabetes (T2D), and dyslipidaemia, which is characterised by excessive fat accumulation …
MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally. They are involved in the regulation of physiological processes, such as adaptation to …