Peptide-tags for site-specific protein labelling in vitro and in vivo

J Lotze, U Reinhardt, O Seitz… - Molecular …, 2016 - pubs.rsc.org
Peptide-tags for site-specific protein labelling in vitro and in vivo - Molecular BioSystems (RSC
Publishing) DOI:10.1039/C6MB00023A Royal Society of Chemistry View PDF VersionPrevious …

Whole-animal connectomes of both Caenorhabditis elegans sexes

SJ Cook, TA Jarrell, CA Brittin, Y Wang, AE Bloniarz… - Nature, 2019 - nature.com
Abstract Knowledge of connectivity in the nervous system is essential to understanding its
function. Here we describe connectomes for both adult sexes of the nematode …

Synaptogenesis: unmasking molecular mechanisms using Caenorhabditis elegans

K Mizumoto, Y Jin, JL Bessereau - Genetics, 2023 - academic.oup.com
The nematode Caenorhabditis elegans is a research model organism particularly suited to
the mechanistic understanding of synapse genesis in the nervous system. Armed with …

Mapping the dynamics and nanoscale organization of synaptic adhesion proteins using monomeric streptavidin

I Chamma, M Letellier, C Butler, B Tessier… - Nature …, 2016 - nature.com
The advent of super-resolution imaging (SRI) has created a need for optimized labelling
strategies. We present a new method relying on fluorophore-conjugated monomeric …

Sex-specific pruning of neuronal synapses in Caenorhabditis elegans

M Oren-Suissa, EA Bayer, O Hobert - Nature, 2016 - nature.com
Whether and how neurons that are present in both sexes of the same species can
differentiate in a sexually dimorphic manner is not well understood. A comparison of the …

Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior

V Pechuk, G Goldman, Y Salzberg, AH Chaubey… - Current biology, 2022 - cell.com
The effect of the detailed connectivity of a neural circuit on its function and the resulting
behavior of the organism is a key question in many neural systems. Here, we study the …

Toolkits for detailed and high-throughput interrogation of synapses in C. elegans

M Majeed, H Han, K Zhang, WX Cao, CP Liao… - Elife, 2024 - elifesciences.org
Visualizing synaptic connectivity has traditionally relied on time-consuming electron
microscopy-based imaging approaches. To scale the analysis of synaptic connectivity …

Ubiquitin-dependent regulation of a conserved DMRT protein controls sexually dimorphic synaptic connectivity and behavior

EA Bayer, RC Stecky, L Neal, PS Katsamba, G Ahlsen… - Elife, 2020 - elifesciences.org
Sex-specific synaptic connectivity is beginning to emerge as a remarkable, but little explored
feature of animal brains. We describe here a novel mechanism that promotes sexually …

Synaptic protein degradation controls sexually dimorphic circuits through regulation of DCC/UNC-40

Y Salzberg, V Pechuk, A Gat, H Setty, S Sela… - Current biology, 2020 - cell.com
Sexually dimorphic circuits underlie behavioral differences between the sexes, yet the
molecular mechanisms involved in their formation are poorly understood. We show here that …

[HTML][HTML] The synaptic basis for sexual dimorphism in the invertebrate nervous system

Y Salzberg, R Haque, M Oren-Suissa - Current Opinion in Neurobiology, 2023 - Elsevier
Many animal behaviors are manifested differently in the two sexes of a given species, but
how such sexual dimorphism is imprinted in the nervous system is not always clear. One …