Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis

AR Maher, M Maglione, S Bagley, M Suttorp, JH Hu… - Jama, 2011 - jamanetwork.com
Context Atypical antipsychotic medications are commonly used for off-label conditions such
as agitation in dementia, anxiety, and obsessive-compulsive disorder. Objective To perform …

Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm

DT Maust, HM Kim, LS Seyfried, C Chiang… - JAMA …, 2015 - jamanetwork.com
Importance Antipsychotic medications are associated with increased mortality in older adults
with dementia, yet their absolute effect on risk relative to no treatment or an alternative …

Nonpharmacologic management of behavioral symptoms in dementia

LN Gitlin, HC Kales, CG Lyketsos - Jama, 2012 - jamanetwork.com
Behavioral symptoms such as repetitive speech, wandering, and sleep disturbances are a
core clinical feature of Alzheimer disease and related dementias. If untreated, these …

Comparative efficacy of interventions for aggressive and agitated behaviors in dementia: a systematic review and network meta-analysis

JA Watt, Z Goodarzi, AA Veroniki, V Nincic… - Annals of internal …, 2019 - acpjournals.org
Background: Both pharmacologic and nonpharmacologic interventions are used to treat
neuropsychiatric symptoms in persons with dementia. Purpose: To summarize the …

Risk of mortality among individual antipsychotics in patients with dementia

HC Kales, HM Kim, K Zivin… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: The use of antipsychotics to treat the behavioral symptoms of dementia is
associated with greater mortality. The authors examined the mortality risk of individual …

Off-label prescribing of antipsychotics in adults, children and elderly individuals: a systematic review of recent prescription trends

L Carton, O Cottencin… - Current …, 2015 - ingentaconnect.com
Introduction: New antipsychotics continuously arrive on the market, which thereby influences
the approved and off-label prescribing (OLP) schemes. We aimed to identify the recent …

Association of the Centers for Medicare & Medicaid Services' national partnership to improve dementia care with the use of antipsychotics and other psychotropics in …

DT Maust, HM Kim, C Chiang… - JAMA internal medicine, 2018 - jamanetwork.com
Importance The Centers for Medicare & Medicaid Services' National Partnership to Improve
Dementia Care in Nursing Homes (hereafter referred to as the partnership) was established …

Antipsychotic use in dementia: is there a problem and are there solutions?

J Kirkham, C Sherman, C Velkers… - The Canadian …, 2017 - journals.sagepub.com
Antipsychotics are necessary for many older adults to treat major mental illnesses or reduce
distressing psychiatric symptoms. Current controversy exists over the role of antipsychotics …

Pharmacological treatments for neuropsychiatric symptoms of dementia in long-term care: a systematic review

DP Seitz, SS Gill, N Herrmann, S Brisbin… - International …, 2013 - cambridge.org
Background: Medications are frequently prescribed for neuropsychiatric symptoms (NPS)
associated with dementia, although information on the efficacy and safety of medications for …