Protein engineering of pores for separation, sensing, and sequencing
Proteins are critical to cellular function and survival. They are complex molecules with
precise structures and chemistries, which allow them to serve diverse functions for …
precise structures and chemistries, which allow them to serve diverse functions for …
[HTML][HTML] Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response
The integrated stress response (ISR) protects cells from a variety of insults. Once elicited
(eg, by virus infections), it eventually leads to the block of mRNA translation. Central to the …
(eg, by virus infections), it eventually leads to the block of mRNA translation. Central to the …
[HTML][HTML] A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling
RE Lawrence, SR Shoemaker, A Deal… - Nature Chemical …, 2024 - nature.com
The integrated stress response (ISR) enables cells to survive a variety of acute stresses, but
chronic activation of the ISR underlies age-related diseases. ISR signaling downregulates …
chronic activation of the ISR underlies age-related diseases. ISR signaling downregulates …
Both rapid hyperplasia and hypertrophy promoted skeletal muscle growth in mandarin fish Siniperca chuatsi, compared to big-eye mandarin fish Siniperca kneri
X Yao, C Chen, K Nyirenda, J Zheng, Y Zhao, S Tang… - Aquaculture, 2025 - Elsevier
As important cultured fishes in China, mandarin fish, Siniperca chuatsi and big-eye
mandarin fish, Siniperca kneri share similar external morphology and genomes, but have …
mandarin fish, Siniperca kneri share similar external morphology and genomes, but have …
A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling
RE Lawrence, S Shoemaker, A Deal, S Sangwan… - bioRxiv, 2022 - biorxiv.org
Abstract The Integrated Stress Response (ISR) enables cells to survive a variety of acute
stresses, but chronic activation of the ISR underlies age-related diseases. ISR signaling …
stresses, but chronic activation of the ISR underlies age-related diseases. ISR signaling …
The role of eIF2Bα in the integrity of eIF2B bodies
MIR de Oliveira - 2023 - search.proquest.com
The eukaryotic initiation factor 2B (eIF2B) is a multisubunit protein composed of two sets of
five subunits (α-ε) forming a heterodecamer. eIF2B is a guanine exchange factor (GEF) …
five subunits (α-ε) forming a heterodecamer. eIF2B is a guanine exchange factor (GEF) …
[PDF][PDF] THE ROLE OF RNA BINDING PROTEINS AND CRISPR/CAS9 AS A GENE EDITING TOOL IN DROSOPHILA NOCICEPTION
EFR Silva - 2023 - libres.uncg.edu
Pain is generally understood as a negative emotional experience that occurs in response to
an extreme stimulus, whether it be thermal, mechanical, or chemical in nature. Indeed, the …
an extreme stimulus, whether it be thermal, mechanical, or chemical in nature. Indeed, the …