Obesity and bone: a complex relationship

G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can
conclude from this review is that the increase in body weight causes an increase in BMD …

The role of osteoclast energy metabolism in the occurrence and development of osteoporosis

W Da, L Tao, Y Zhu - Frontiers in endocrinology, 2021 - frontiersin.org
In recent decades, the mechanism underlying bone metabolic disorders based on energy
metabolism has been heavily researched. Bone resorption by osteoclasts plays an important …

Cardiovascular disease diagnosis from DXA scan and retinal images using deep learning

HRH Al-Absi, MT Islam, MA Refaee, MEH Chowdhury… - Sensors, 2022 - mdpi.com
Cardiovascular diseases (CVD) are the leading cause of death worldwide. People affected
by CVDs may go undiagnosed until the occurrence of a serious heart failure event such as …

Saturation effect of body mass index on bone mineral density in adolescents of different ages: a population-based study

Y Ouyang, Y Quan, C Guo, S Xie, C Liu… - Frontiers in …, 2022 - frontiersin.org
Background Adolescence is a critical period for bone development, and peak bone mass
may be reached in late adolescence. Boosting bone accumulation at this time can help …

Menopause—Biology, consequences, supportive care, and therapeutic options

SR Davis, JA Pinkerton, N Santoro, T Simoncini - Cell, 2023 - cell.com
Menopause is the cessation of ovarian function, with loss of reproductive hormone
production and irreversible loss of fertility. It is a natural part of reproductive aging. The …

Obesity, bone loss, and periodontitis: the interlink

P Zhao, A Xu, WK Leung - Biomolecules, 2022 - mdpi.com
Obesity and periodontitis are both common health concerns that have given rise to
considerable economic and societal burden worldwide. There are established negative …

The roles of epigenetics regulation in bone metabolism and osteoporosis

F Xu, W Li, X Yang, L Na, L Chen, G Liu - Frontiers in cell and …, 2021 - frontiersin.org
Osteoporosis is a metabolic disease characterized by decreased bone mineral density and
the destruction of bone microstructure, which can lead to increased bone fragility and risk of …

Osteopontin, a bridge links osteoarthritis and osteoporosis

RJ Bai, YS Li, FJ Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Osteoarthritis (OA) is the most prevalent joint disease characterized by degradation of
articular cartilage, inflammation, and changes in periarticular and subchondral bone of …

Adipokines at the crossroads of obesity and mesenchymal stem cell therapy

DV Pham, TK Nguyen, PH Park - Experimental & Molecular Medicine, 2023 - nature.com
Mesenchymal stem cell (MSC) therapy is an emerging treatment strategy to counteract
metabolic syndromes, including obesity and its comorbid disorders. However, its …

Endocrinal metabolic regulation on the skeletal system in post-menopausal women

S Thapa, A Nandy, E Rendina-Ruedy - Frontiers in Physiology, 2022 - frontiersin.org
Osteoporosis is a common endocrinologic disorder characterized as a chronic bone loss
condition. Sexual dimorphism is ubiquitous in the incidence of osteoporosis with post …