A harmonized balance between positive and negative regulation of pattern recognition
receptor (PRR)-initiated immune responses is required to achieve the most favorable …

In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …

Cytosolic mitochondrial DNA (mtDNA) activates cGAS-mediated antiviral immune
responses, but the mechanism by which RNA viruses stimulate mtDNA release remains …

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever
caused by a tick-borne banyangvirus and is associated with high fatality. Despite increasing …

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease
with high fatality. Poor prognosis of SFTS has been associated with dysregulated host …

RIG-I-like receptors (RLRs) are crucial for pathogen detection and triggering immune
responses and have immense physiological importance. In this review, we first summarize …

Severe fever with thrombocytopenia syndrome (SFTS) has been acknowledged as an
emerging infectious disease that is caused by the SFTS virus (SFTSV). The main clinical …

The RIG-I–like receptors (RLRs) retinoic acid–inducible gene I protein (RIG-I) and
melanoma differentiation–associated protein 5 (MDA5) are cytosolic pattern recognition …

Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by Dabie bandavirus
(SFTSV), is an emerging infectious disease first identified in China. Since its discovery …

Dabie bandavirus (severe fever with thrombocytopenia syndrome virus [SFTSV]) induces an
immunopathogenic disease with a high fatality rate; however, the mechanisms underlying its …