Anti-obesity drug discovery: advances and challenges

TD Müller, M Blüher, MH Tschöp… - Nature Reviews Drug …, 2022 - nature.com
Enormous progress has been made in the last half-century in the management of diseases
closely integrated with excess body weight, such as hypertension, adult-onset diabetes and …

Hypertension in diabetes: an update of basic mechanisms and clinical disease

G Jia, JR Sowers - Hypertension, 2021 - Am Heart Assoc
Epidemiological studies have documented that insulin resistance and diabetes not only
constitute metabolic abnormalities but also predispose to hypertension, vascular stiffness …

[HTML][HTML] A wearable electrochemical biosensor for the monitoring of metabolites and nutrients

M Wang, Y Yang, J Min, Y Song, J Tu… - Nature Biomedical …, 2022 - nature.com
Wearable non-invasive biosensors for the continuous monitoring of metabolites in sweat can
detect a few analytes at sufficiently high concentrations, typically during vigorous exercise so …

[HTML][HTML] Diet quality and risk and severity of COVID-19: a prospective cohort study

J Merino, AD Joshi, LH Nguyen, ER Leeming, M Mazidi… - Gut, 2021 - gut.bmj.com
Objective Poor metabolic health and unhealthy lifestyle factors have been associated with
risk and severity of COVID-19, but data for diet are lacking. We aimed to investigate the …

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2—care pathways, treatment, and follow-up

Cardiovascular Research, 2022 - academic.oup.com
Aims Since its emergence in early 2020, the novel severe acute respiratory syndrome
coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Plasma markers of disrupted gut permeability in severe COVID-19 patients

LB Giron, H Dweep, X Yin, H Wang, M Damra… - Frontiers in …, 2021 - frontiersin.org
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of
severity during respiratory-related diseases. Lung injury causes systemic inflammation …

Airborne transmission of COVID-19: aerosol dispersion, lung deposition, and virus-receptor interactions

YY Zuo, WE Uspal, T Wei - ACS nano, 2020 - ACS Publications
Coronavirus disease 2019 (COVID-19), due to infection by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is now causing a global pandemic. Aerosol …

Visceral fat is associated to the severity of COVID-19

G Favre, K Legueult, C Pradier, C Raffaelli, C Ichai… - Metabolism, 2021 - Elsevier
Background Excess visceral fat (VF) or high body mass index (BMI) is risk factors for severe
COVID-19. The receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Healthy food retail during the COVID-19 pandemic: challenges and future directions

LA Leone, S Fleischhacker… - International journal of …, 2020 - mdpi.com
Disparities in dietary behaviors have been directly linked to the food environment, including
access to retail food outlets. The Coronavirus Disease of 2019 (COVID-19) pandemic has …