Self‐assembling peptide‐based hydrogels for wound tissue repair

T Guan, J Li, C Chen, Y Liu - Advanced Science, 2022 - Wiley Online Library
Wound healing is a long‐term, multistage biological process that includes hemostasis,
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …

Self-assembling prodrugs

AG Cheetham, RW Chakroun, W Ma… - Chemical Society Reviews, 2017 - pubs.rsc.org
Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …

Self-assembled peptide drug delivery systems

J Yang, HW An, H Wang - ACS Applied Bio Materials, 2020 - ACS Publications
Over the past several decades, rapid advances have been made in the application of
nanomaterials in the biomedical field including bioimaging and drug delivery. Owing to the …

In Situ Forming, Enzyme-Responsive Peptoid-Peptide Hydrogels: An Advanced Long-Acting Injectable Drug Delivery System

SM Coulter, S Pentlavalli, Y An, LK Vora… - Journal of the …, 2024 - ACS Publications
Long-acting drug delivery systems are promising platforms to improve patient adherence to
medication by delivering drugs over sustained periods and removing the need for patients to …

Bioinspired hydrogels as platforms for life-science applications: Challenges and opportunities

M Bercea - Polymers, 2022 - mdpi.com
Hydrogels, as interconnected networks (polymer mesh; physically, chemically, or dynamic
crosslinked networks) incorporating a high amount of water, present structural …

Drug delivery with designed peptide assemblies

MJ Sis, MJ Webber - Trends in pharmacological sciences, 2019 - cell.com
Self-assembly of designed synthetic peptides is a versatile strategy to generate functional
materials for many applications. Given the biological relevance of their amino acid …

Supramolecular tubustecan hydrogel as chemotherapeutic carrier to improve tumor penetration and local treatment efficacy

F Wang, H Su, R Lin, RW Chakroun, MK Monroe… - ACS …, 2020 - ACS Publications
Local chemotherapy is a clinically proven strategy in treating malignant brain tumors. Its
benefits, however, are largely limited by the rapid release and clearance of therapeutic …

Controlled drug delivery with nanoassemblies of redox-responsive prodrug and polyprodrug amphiphiles

Z Deng, S Liu - Journal of controlled Release, 2020 - Elsevier
Self-assembled nanostructures are highly promising for controlled delivery of therapeutic
and diagnostic agents. However, for conventional drug delivery nanosystems, there exist …

[HTML][HTML] Bioactive scaffolds for regeneration of cartilage and subchondral bone interface

C Deng, H Zhu, J Li, C Feng, Q Yao, L Wang… - Theranostics, 2018 - ncbi.nlm.nih.gov
The cartilage lesion resulting from osteoarthritis (OA) always extends into subchondral bone.
It is of great importance for simultaneous regeneration of two tissues of cartilage and …

Self-assembling peptides as vectors for local drug delivery and tissue engineering applications

C Karavasili, DG Fatouros - Advanced drug delivery reviews, 2021 - Elsevier
Molecular self-assembly has forged a new era in the development of advanced biomaterials
for local drug delivery and tissue engineering applications. Given their innate …