Recombinant vaccines in 2022: a perspective from the cell factory

MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Biosensors based on the binding events of nitrilotriacetic acid–metal complexes

L Zhu, Y Chang, Y Li, M Qiao, L Liu - Biosensors, 2023 - mdpi.com
Molecular immobilization and recognition are two key events for the development of
biosensors. The general ways for the immobilization and recognition of biomolecules …

Pyrolysis regulation of ZIF-8 to construct a robust multifunctional N-doped macroporous carbon for lipase immobilization

H Zhou, Y Shi, L Dai, D Liu, W Du - Chemical Engineering Journal, 2023 - Elsevier
Pyrolyzing ZIF-8 into N-doped carbon is now inspiring new potential of ZIF-8 for extensive
applications. However, the exploration of such ZIF-8-derived carbon for biotechnological …

[HTML][HTML] Protein features instruct the secretion dynamics from metal-supported synthetic amyloids

E Parladé, JM Sánchez, H López-Laguna… - International journal of …, 2023 - Elsevier
Hexahistidine-tagged proteins can be clustered by divalent cations into self-containing,
dynamic protein depots at the microscale, which under physiological conditions leak …

Probing the Biosafety of Implantable Artificial Secretory Granules for the Sustained Release of Bioactive Proteins

P Álamo, E Parladé, MTP Favaro… - … applied materials & …, 2023 - ACS Publications
Among bio-inspired protein materials, secretory protein microparticles are of clinical interest
as self-contained, slow protein delivery platforms that mimic secretory granules of the human …

Tumor microenvironment-responsive histidine modified-hyaluronic acid-based MnO2 as in vivo MRI contrast agent

JY Hong, YG Lim, YJ Song, K Park - International Journal of Biological …, 2023 - Elsevier
Tumor microenvironment (TME)-responsive manganese dioxide (MnO 2) nanoparticles as a
good T 1 contrast agent could reduce unwanted toxicity and improve the accuracy of cancer …

Construction of catalase@ hollow silica nanosphere: Catalase with immobilized but not rigid state for improving catalytic performances

Y Du, L Zhao, Z Geng, Z Huo, H Li, X Shen… - International Journal of …, 2024 - Elsevier
Enzyme immobilization usually make use of nanomaterials to hold up biocatalysis stability in
various unamiable reaction conditions, but also lead large discount on enzyme activity …

Biofabrication of functional protein nanoparticles through simple His-tag engineering

H López-Laguna, JM Sanchez… - ACS sustainable …, 2021 - ACS Publications
We have developed a simple, robust, and fully transversal approach for the a-la-carte
fabrication of functional multimeric nanoparticles with potential biomedical applications …

A multifunctional drug delivery system based on switchable peptide-stabilized emulsions

D Boas, A van Teijlingen, Z Shpilt, DE Shalev… - Chem, 2024 - cell.com
Emulsions are commonly used for drug delivery, yet they are usually limited to exclusively
delivering either lipophilic or hydrophilic compounds. This separation negates possible …

Direct purification and immobilization of his-tagged enzymes using unmodified nickel ferrite NiFe2O4 magnetic nanoparticles

ECHT Lau, KC Dodds, C McKenna, RM Cowan… - Scientific Reports, 2023 - nature.com
Purification of valuable engineered proteins and enzymes can be laborious, costly, and
generating large amount of chemical waste. Whilst enzyme immobilization can enhance …