The erasure of epigenetic modifications across the genome of somatic cells is an essential
requirement during their reprogramming into induced pluripotent stem cells (iPSCs). Vitamin …

DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …

Loss-of-function mutations of DNAJC6, encoding HSP40 auxilin, have recently been
identified in patients with early-onset Parkinson's disease (PD). To study the roles of …

Parkinson's disease (PD) is the second most common neurodegenerative disease in the
elderly, which is clinically characterized by bradykinesia, resting tremor, abnormal posture …

Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by progressive loss of dopaminergic neurons in the substantia nigra of the …

There is a widespread belief that neurogenesis exists in adult human brain, especially in the
dentate gyrus, and it is to be maintained and, if possible, augmented with different stimuli …

Ascorbic acid, a water-soluble vitamin, is highly concentrated in the brain and participates in
neuronal modulation and regulation of central nervous system (CNS) homeostasis. Ascorbic …

Gestational diet has a long-dated effect not only on the disease risk in offspring but also on
the occurrence of future neurological diseases. During ontogeny, changes in the epigenetic …

Ischemic stroke is one of the most leading diseases causing death/long-term disability
worldwide. Activating endogenous neural stem/progenitors cells (NSPCs), lining in the …

Epigenetic modifications are crucial regulators of gene expression that critically impact cell
lineage differentiation, survival, and proliferation, and dysregulations are commonly …