Dengue is widespread throughout the tropics and local spatial variation in dengue virus
transmission is strongly influenced by rainfall, temperature, urbanization and distribution of …

Dengue virus (DENV) is a mosquito-borne member of the Flavivirus genus and includes four
serotypes (DENV-1, DENV-2, DENV-3, and DENV-4), each of which is capable of causing …

The number of cases of severe dengue disease continues to grow in endemic areas of
southeast Asia, Central and South America, and other subtropical regions. Children bear the …

Introduction: Dengue virus is a global health threat, with approximately 390 million dengue
infections annually. Efficient vaccines for dengue prevention are currently lacking. This …

Dengue, a rapidly spreading mosquito-borne human viral disease caused by dengue virus
(DENV), is a public health concern in tropical and subtropical areas due to its expanding …

Dengue virus (DENV) is a significant cause of morbidity and mortality in tropical and
subtropical regions, causing hundreds of millions of infections each year. Infections range …

Each of the DENV serotypes can cause the full spectrum of dengue illness. Epidemiological
studies have implicated preexisting heterotypic DENV antibody as a risk factor for more …

Dengue is one of the most important emerging vector-borne viral diseases. There are four
serotypes of dengue viruses (DENV), each of which is capable of causing self-limited …

Infection with dengue virus (DENV) is the most rapidly spreading mosquito-borne viral
disease in the world. The clinical spectrum of dengue, caused by any of the four serotypes of …

The development of a safe and efficient dengue vaccine represents a global challenge in
public health. Chimeric dengue viruses (DENV) based on an attenuated flavivirus have …