Exposure of blood to a foreign surface in the form of a diagnostic or therapeutic biomaterial
device or implanted cells or tissue elicits an immediate, evolutionarily conserved …

Psoriasis is a chronic inflammatory skin disease with a prevalence of 0.14% to 1.99%. The
underlying pathology is mainly driven by the abnormal immune responses including …

Lipid-lowering agents and antiplatelet drugs are guideline-recommended standard
treatment for secondary prevention of acute thrombotic events in patients with increased …

Atherosclerosis-related coronary artery disease (CAD) is the leading cause of mortality and
morbidity worldwide. This requires effective primary and secondary prevention in reducing …

The imbalance between reactive oxygen species (ROS) synthesis and their scavenging by
anti-oxidant defences is the common soil of many disorders, including …

Atherosclerosis-related coronary artery disease (CAD) is one of the leading sources of
mortality and morbidity in the world. Primary and secondary prevention appear crucial to …

Over the last decade, the incidence of infective endocarditis (IE) has increased, with a
change in the frequency of causative bacteria. Early evidence has substantially …

Hemorrhage is the leading cause of trauma-related deaths, in hospital and prehospital
settings. Hemostasis is a complex mechanism that involves a cascade of clotting factors and …

Background Platelets are key players in the pathophysiology of coronary artery disease
(CAD) and platelet hyperreactivity leads to increased risk of developing adverse …

Platelets are one of the coagulation cells. When platelet activation occurs, many mediators
are released and affect endothelial cells (ECs) and lead to endothelial dysfunction (ED). ED …