A bottom-up view of antimicrobial resistance transmission in developing countries

OO Ikhimiukor, EE Odih, P Donado-Godoy… - Nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is tracked most closely in clinical settings and high-income
countries. However, resistant organisms thrive globally and are transmitted to and from …

Methicillin-resistant Staphylococcus aureus: molecular characterization, evolution, and epidemiology

S Lakhundi, K Zhang - Clinical microbiology reviews, 2018 - Am Soc Microbiol
Staphylococcus aureus, a major human pathogen, has a collection of virulence factors and
the ability to acquire resistance to most antibiotics. This ability is further augmented by …

Exploring the temporal structure of heterochronous sequences using TempEst (formerly Path-O-Gen)

A Rambaut, TT Lam, L Max Carvalho… - Virus …, 2016 - academic.oup.com
Gene sequences sampled at different points in time can be used to infer molecular
phylogenies on a natural timescale of months or years, provided that the sequences in …

Antimicrobial resistance in humans, livestock and the wider environment

M Woolhouse, M Ward… - … Transactions of the …, 2015 - royalsocietypublishing.org
Antimicrobial resistance (AMR) in humans is inter-linked with AMR in other populations,
especially farm animals, and in the wider environment. The relatively few bacterial species …

A new perspective on lysogeny: prophages as active regulatory switches of bacteria

R Feiner, T Argov, L Rabinovich, N Sigal… - Nature Reviews …, 2015 - nature.com
Unlike lytic phages, temperate phages that enter lysogeny maintain a long-term association
with their bacterial host. In this context, mutually beneficial interactions can evolve that …

Basis of virulence in enterotoxin-mediated staphylococcal food poisoning

EL Fisher, M Otto, GYC Cheung - Frontiers in microbiology, 2018 - frontiersin.org
The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that
share structural and functional similarities and possess potent superantigenic activity …

Staphylococcus aureus in Animals

AF Haag, JR Fitzgerald, JR Penadés - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a mammalian commensal and opportunistic pathogen that
colonizes niches such as skin, nares and diverse mucosal membranes of about 20-30% of …

Population genomics of bacterial host adaptation

SK Sheppard, DS Guttman, JR Fitzgerald - Nature Reviews Genetics, 2018 - nature.com
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …

[HTML][HTML] Methicillin-resistant Staphylococcus aureus among animals: current overview

M Aires-de-Sousa - Clinical Microbiology and Infection, 2017 - Elsevier
Currently, methicillin-resistant Staphylococcus aureus (MRSA) is a universal threat. After
being well established in the healthcare setting, it has emerged in the community among …

Livestock-associated MRSA: the impact on humans

C Cuny, LH Wieler, W Witte - Antibiotics, 2015 - mdpi.com
During the past 25 years an increase in the prevalence of methicillin-resistant
Staphylococcus aureus (HA-MRSA) was recorded worldwide. Additionally, MRSA infections …