The orbitofrontal cortex: reward, emotion and depression

ET Rolls, W Cheng, J Feng - Brain communications, 2020 - academic.oup.com
The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

The self in context: brain systems linking mental and physical health

L Koban, PJ Gianaros, H Kober… - Nature Reviews …, 2021 - nature.com
Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

Meta-reinforcement learning via orbitofrontal cortex

R Hattori, NG Hedrick, A Jain, S Chen, H You… - Nature …, 2023 - nature.com
The meta-reinforcement learning (meta-RL) framework, which involves RL over multiple
timescales, has been successful in training deep RL models that generalize to new …

The neural basis of reversal learning: An updated perspective

A Izquierdo, JL Brigman, AK Radke, PH Rudebeck… - Neuroscience, 2017 - Elsevier
Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

The neuroscience of placebo effects: connecting context, learning and health

TD Wager, LY Atlas - Nature Reviews Neuroscience, 2015 - nature.com
Placebo effects are beneficial effects that are attributable to the brain–mind responses to the
context in which a treatment is delivered rather than to the specific actions of the drug. They …

Executive functions

I Cristofori, S Cohen-Zimerman, J Grafman - Handbook of clinical neurology, 2019 - Elsevier
Executive functions (EFs) include high-order cognitive abilities such as working memory,
inhibitory control, cognitive flexibility, planning, reasoning, and problem solving. EFs enable …

Neural correlates of maintaining one's political beliefs in the face of counterevidence

JT Kaplan, SI Gimbel, S Harris - Scientific reports, 2016 - nature.com
People often discount evidence that contradicts their firmly held beliefs. However, little is
known about the neural mechanisms that govern this behavior. We used neuroimaging to …

What the orbitofrontal cortex does not do

TA Stalnaker, NK Cooch, G Schoenbaum - Nature neuroscience, 2015 - nature.com
The number of papers about the orbitofrontal cortex (OFC) has grown from 1 per month in
1987 to a current rate of over 50 per month. This publication stream has implicated the OFC …

A meta-analysis of heart rate variability and neuroimaging studies: implications for heart rate variability as a marker of stress and health

JF Thayer, F Åhs, M Fredrikson, JJ Sollers III… - Neuroscience & …, 2012 - Elsevier
The intimate connection between the brain and the heart was enunciated by Claude
Bernard over 150 years ago. In our neurovisceral integration model we have tried to build on …

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

RZ Goldstein, ND Volkow - Nature reviews neuroscience, 2011 - nature.com
The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …