The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Stroke is a major cause of death and disability worldwide. Yet therapeutic strategies
available to treat stroke are very limited. There is an urgent need to develop novel …

Despite low levels of cannabinoid receptor type 2 (CB2R) expression in the central nervous
system in human and rodents, a growing body of evidence shows CB2R involvement in …

Inflammation is an important mediator of secondary neurological injury after traumatic brain
injury (TBI). Endocannabinoids, endogenously produced arachidonate based lipids, have …

Highlights•The endocannabinoid system is involved in all aspects of the biology of neural
stem cells.•Selective CB 1 and CB 2 agonism produces pro-neurogenic effects in different …

The substantial clinical burden and disability after stroke injury urges the need to explore
therapeutic solutions. Recent compelling evidence supports that neurogenesis persists in …

Parkinson's disease (PD) is a neurodegenerative disease usually caused by
neuroinflammation, oxidative stress and other etiologies. Recent studies have found that the …

Apart from being used as a medicine, cannabis or marijuana is the most widely abused
recreational drug all over the world. The legalization and decriminalization of cannabis in …

The cannabinoid receptor 2 (CB2R) has been considered as a potential therapeutic target to
ameliorate the neuroinflammation and cognitive impairments of Alzheimer's disease (AD) …

While cannabis is perceived as a relatively safe drug by the public, accumulating clinical
data suggest detrimental cardiovascular effects of cannabinoids. Cannabis has been …