[HTML][HTML] Experimental animal models of drug-induced sensorineural hearing loss: a narrative review

X Lin, J Luo, J Tan, L Yang, M Wang… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Objective This narrative review describes experimental animal models of sensorineural
hearing loss (SNHL) caused by ototoxic agents. Background SNHL primarily results from …

Induced pluripotent stem cells, a stepping stone to in vitro human models of hearing loss

MB Durán-Alonso, H Petković - Cells, 2022 - mdpi.com
Hearing loss is the most prevalent sensorineural impairment in humans. Yet despite very
active research, no effective therapy other than the cochlear implant has reached the clinic …

Disruption of glutamate release and uptake-related protein expression after noise-induced synaptopathy in the cochlea

K Ma, A Zhang, X She, H Yang, K Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
High-intensity noise can cause permanent hearing loss; however, short-duration medium-
intensity noise only induces a temporary threshold shift (TTS) and damages synapses …

Cell transplantation to restore lost auditory nerve function is a realistic clinical opportunity

T Sekiya, MC Holley - Cell Transplantation, 2021 - journals.sagepub.com
Hearing is one of our most important means of communication. Disabling hearing loss (DHL)
is a long-standing, unmet problem in medicine, and in many elderly people, it leads to social …

The use of animal models to study cell transplantation in neuropathic hearing loss

L Abbas, MN Rivolta - Hearing Research, 2019 - Elsevier
Auditory neuropathy (AN) is a form of sensorineural deafness specifically affecting the
conduction of the nerve impulse from the cochlear hair cells to the auditory centres of the …

Harderian gland-derived stem cells as a cytotherapy in a guinea pig model of carboplatin-induced hearing loss

HHH Abd El Raouf, RA Galhom, MHM Ali… - Journal of Chemical …, 2019 - Elsevier
Background Stem cells therapy of hearing loss is a challenging field due to lacking self-
regenerative capacity of cochlea. Harderian gland of guinea pigs was thought to harbour a …

Digoxin induces inner ear damage

H OHGITA, A TAURA, K NISHIMURA… - AINO …, 2022 - aino.repo.nii.ac.jp
Auditory neuropathy is a hearing disorder in which the inner ear can detect sounds, but has
a problem with sending sounds to the brain. The main pathology might be the disorder …

[引用][C] Induced Pluripotent Stem Cells, a Stepping Stone to In Vitro Human Models of Hearing Loss. Cells 2022, 11, 3331

MB Durán-Alonso, H Petkovic - 2022 - europepmc.org
Hearing loss is the most prevalent sensorineural impairment in humans. Yet despite very
active research, no effective therapy other than the cochlear implant has reached the clinic …