BackgroundEarly intervention services for psychosis aim to detect emergent symptoms,
reduce the duration of untreated psychosis, and improve access to effective treatments …

Background To systematically review evidence of the effects of the duration of untreated
depression on the clinical outcomes of patients suffering from Unipolar Major Depression …

Care and outcomes for people with schizophrenia have improved in recent years, but further
progress is needed to help more individuals achieve an independent and fulfilled life. This …

Subtle features in people's everyday language may harbor the signs of future mental illness.
Machine learning offers an approach for the rapid and accurate extraction of these signs …

Despite years of research, the mechanisms governing the onset, relapse, symptomatology,
and treatment of schizophrenia (SZ) remain elusive. The lack of appropriate analytic tools to …

During recent decades, interest in the prevention of mental illnesses has increased.
Improved diagnostic tools, the advent of atypical antipsychotic medications and the …

Background Delayed treatment for first episodes of psychosis predicts worse outcomes. We
hypothesised that delaying treatment makes all symptoms more refractory, with harm …

The first psychotic episode is classically viewed as a critical period which management is
important in determining the long-term outcome of the schizophrenia (SCZ). For this reason …

BACKGROUND: Cognitive deficits occur early in the course of psychosis, are mostly stable,
and have been identified as potential functional prognostic markers. Previous reviews of …

The negative symptoms of schizophrenia can be divided into two domains. Avolition/apathy
includes the individual symptoms of avolition, asociality and anhedonia. Diminished …