Coumarin derivatives are important class of natural plant metabolites that offer variety of
biological activities. They can also be derived synthetically, and a wide variety of synthetic …

Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

Background A large number of studies have recently reported that, because of their
significant biological and pharmacological properties, heterocyclic compounds and their …

Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Herein, we have developed a novel synthetic route for the synthesis of chromeno [4, 3-d]
pyrido [1, 2-a] pyrimidin-6-one derivatives 8a-q using an acid ionic liquid [CMMIM][BF4–] 4 …

There are over 100 commercially available drugs for the handling of cancer, but only a
handful of them have high specificity, leading to a variety of side effects. The past few …

1, 2, 4-Triazole derivatives possess promising in vitro and in vivo anticancer activity, and
many anticancer agents such as fluconazole, tebuconazole, triadimefon, and ribavirin bear a …

Molecular hybridization represents a new approach in drug discovery in which specific
chromophores are strategically combined to create novel drugs with enhanced therapeutic …