[HTML][HTML] Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

M Warszyńska, P Repetowski, JM Dąbrowski - Coordination Chemistry …, 2023 - Elsevier
Innovative anticancer therapies based on the activation of the immune system offer promise
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …

Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

JM Dąbrowski, B Pucelik, A Regiel-Futyra… - Coordination Chemistry …, 2016 - Elsevier
Applications of metalloporphyrins and related molecules have been extensively pursued in
the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This …

Reactive oxygen species in photodynamic therapy: mechanisms of their generation and potentiation

JM Dąbrowski - Advances in inorganic chemistry, 2017 - Elsevier
Reactive oxygen species (ROS) play key roles in cell signaling systems and homeostasis,
and they are also fundamental to photodynamic therapy (PDT). PDT efficacy can be affected …

Bioinorganic antimicrobial strategies in the resistance era

A Regiel-Futyra, JM Dąbrowski, O Mazuryk… - Coordination Chemistry …, 2017 - Elsevier
Abstract The emergence of Multi-Drug-Resistant (MDR) organisms has become a major
worldwide clinical problem. The extensive and routine use of the first-line antibiotics to …

Photodynamic inactivation of bacteria with porphyrin derivatives: effect of charge, lipophilicity, ROS generation, and cellular uptake on their biological activity in vitro

A Sułek, B Pucelik, M Kobielusz, A Barzowska… - International Journal of …, 2020 - mdpi.com
Resistance of microorganisms to antibiotics has led to research on various therapeutic
strategies with different mechanisms of action, including photodynamic inactivation (PDI). In …

Photodynamic inactivation (PDI) as a promising alternative to current pharmaceuticals for the treatment of resistant microorganisms

B Pucelik, JM Dąbrowski - Advances in inorganic Chemistry, 2022 - Elsevier
Although the whole world is currently observing the global battle against COVID-19, it
should not be underestimated that in the next 30 years, approximately 10 million people per …

Recent advances in polysulfide-based prodrug nanomedicines for cancer therapy

C Wang, W Sui, W Chen, Y Zhang, J Xing… - Coordination Chemistry …, 2024 - Elsevier
Polysulfide bonds, particularly trisulfide and tetrasulfide bonds, are prevalent in the fields of
medicine, pharmacy, and materials science. Polysulfide-based prodrug nanomedicines …

Tuning of organic heterojunction conductivity by the substituents' electronic effects in phthalocyanines for ambipolar gas sensors

Z Şahin, R Meunier-Prest, F Dumoulin, A Kumar… - Sensors and Actuators B …, 2021 - Elsevier
Exploiting organic heterojunction effects in electrical devices are an important strategy to
improve the electrical conductivity, which can be utilized into improving the conductometric …

Far-red-absorbing cationic phthalocyanine photosensitizers: synthesis and evaluation of the photodynamic anticancer activity and the mode of cell death induction

M Machacek, A Cidlina, V Novakova… - Journal of Medicinal …, 2015 - ACS Publications
Novel zinc, magnesium, and metal-free octasubstituted phthalocyanine photosensitizers
bearing [(triethylammonio) ethyl] sulfanyl substituents in the peripheral or nonperipheral …

Synthesis, photo-characterizations, and pre-clinical studies on advanced cellular and animal models of zinc (II) and platinum (II) sulfonyl-substituted phthalocyanines …

P Repetowski, M Warszynska, A Kostecka… - … Applied Materials & …, 2024 - ACS Publications
Two phthalocyanine derivatives tetra-peripherally substituted with tert-butylsulfonyl groups
and coordinating either zinc (II) or platinum (II) ions have been synthesized and …