Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing
based on expanded application of high-throughput in vitro screening and in silico methods …

Prediction of chemical-induced hepatotoxicity in humans from in vitro data continues to be a
significant challenge for the pharmaceutical and chemical industries. Generally …

With the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a
Strategy, the US National Academy of Sciences, in 2007, precipitated a major change in the …

Advances in molecular biology and toxicology are paving the way for major improvements in
the evaluation of the hazards posed by the large number of chemicals found at low levels in …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

The definitive reference in its field, Ecological Risk Assessment, Second Edition details the
latest advances in science and practice. In the fourteen years since the publication of the …

Structured frameworks are extremely useful in promoting transparent, harmonized
approaches to the risk assessment of chemicals. One area where this has been particularly …

Although concentrations of ambient air pollution continue to decline in high-income regions,
epidemiological studies document adverse health effects at levels below current standards …

The risk assessment of pesticide residues in food is based on toxicological evaluation of the
single compounds and no internationally accepted procedure exists for evaluation of …

Dedicated to Professor Paul Morrow, 1922–2013 In respectful and fond memory of a
devoted scientist, inspirational colleague, caring mentor, selfless friend, and in gratitude for …