Number and function of uterine natural killer cells in recurrent miscarriage and implantation failure: a systematic review and meta-analysis

E Von Woon, O Greer, N Shah… - Human …, 2022 - academic.oup.com
BACKGROUND Uterine natural killer cells (uNK) are the most abundant lymphocytes found
in the decidua during implantation and in first trimester pregnancy. They are important for …

[HTML][HTML] Endometrial causes of recurrent pregnancy losses: endometriosis, adenomyosis, and chronic endometritis

P Pirtea, E Cicinelli, R De Nola, D de Ziegler… - Fertility and sterility, 2021 - Elsevier
Chronic inflammatory processes affecting the endometrium, as encountered in
endometriosis, adenomyosis, and chronic endometritis, alter endometrial receptivity. These …

Cyclic decidualization of the human endometrium in reproductive health and failure

B Gellersen, JJ Brosens - Endocrine reviews, 2014 - academic.oup.com
Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

Physiologic events of embryo implantation and decidualization in human and non-human primates

MA Ochoa-Bernal, AT Fazleabas - International journal of molecular …, 2020 - mdpi.com
Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

New insights into mechanisms behind miscarriage

EC Larsen, OB Christiansen, AM Kolte, N Macklon - BMC medicine, 2013 - Springer
Sporadic miscarriage is the most common complication of early pregnancy. Two or three
consecutive pregnancy losses is a less common phenomenon, and this is considered a …

The effects of oxidative stress on female reproduction: a review

A Agarwal, A Aponte-Mellado, BJ Premkumar… - Reproductive biology …, 2012 - Springer
Oxidative stress (OS), a state characterized by an imbalance between pro-oxidant molecules
including reactive oxygen and nitrogen species, and antioxidant defenses, has been …

Uterine natural killer cells: from foe to friend in reproduction

I Díaz-Hernández, D Alecsandru… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Recurrent miscarriage and pre-eclampsia are common reproductive
disorders, but their causes are often unknown. Recent evidence has provided new insight …

Human trophoblast invasion: new and unexpected routes and functions

G Moser, K Windsperger, J Pollheimer… - Histochemistry and cell …, 2018 - Springer
Until recently, trophoblast invasion during human placentation was characterized by and
restricted to invasion into uterine connective tissues and the uterine spiral arteries. The latter …

The decidua—the maternal bed embracing the embryo—maintains the pregnancy

M Mori, A Bogdan, T Balassa, T Csabai… - Seminars in …, 2016 - Springer
The decidua has been known as maternal uterine tissue, which plays essential roles in
protecting the embryo from being attacked by maternal immune cells and provides …