A novel brominated chalcone derivative as a promising multi-target inhibitor against multidrug-resistant Listeria monocytogenes
Foodborne pathogens continue to challenge public health due to their ability to cause
severe illness and their increasing resistance to current antimicrobial treatments. Listeria …
severe illness and their increasing resistance to current antimicrobial treatments. Listeria …
Direct synthesis, characterization, in vitro and in silico studies of simple chalcones as potential antimicrobial and antileishmanial agents
H ur Rashid, S Khan, Irum, A Khan… - Royal Society …, 2024 - royalsocietypublishing.org
Chalcone represents a vital biosynthetic scaffold owing to its numerous therapeutic effects.
The present study was intended to synthesize 17 chalcone derivatives (3a–q) by direct …
The present study was intended to synthesize 17 chalcone derivatives (3a–q) by direct …
Synthesis, spectroscopic characterization, DFT analysis, antibacterial, antifungal, antioxidant, molecular docking, and ADME study of 3, 4-dihydro-2H-napthalen-1-one …
RA Shinde, VA Adole, RA More, BS Jagdale… - Journal of Molecular …, 2025 - Elsevier
Chalcone derivatives were synthesized from 3, 4-dihydro-2H-naphthalen-1-one using a
base-catalyzed Claisen-Schmidt reaction and characterized by FT-IR, ¹H NMR, and ¹³C …
base-catalyzed Claisen-Schmidt reaction and characterized by FT-IR, ¹H NMR, and ¹³C …
Chalcone derived bis-organosilane and its magnetic nanoparticles: Unveiling precision in selective Cu (II) ion detection and elucidating biocompatibility
G Singh, P Malik, S Khurana, P Markan, T Diskit… - … Acta Part A: Molecular …, 2025 - Elsevier
The escalating concern regarding the adverse effects of metal ion toxicity on both human
health and environmental ecosystems necessitates the development of efficient detection …
health and environmental ecosystems necessitates the development of efficient detection …
[HTML][HTML] Position Matters: Effect of Nitro Group in Chalcones on Biological Activities and Correlation via Molecular Docking
AY Hidalgo, N Romero-Ceronio… - Scientia …, 2024 - mdpi.com
A series of nine nitro group-containing chalcones were synthesized to investigate their anti-
inflammatory and vasorelaxant activities via in vivo, ex vivo, and in silico studies. The anti …
inflammatory and vasorelaxant activities via in vivo, ex vivo, and in silico studies. The anti …
Synergistic activity between conventional antifungals and chalcone-derived compound against dermatophyte fungi and Candida spp.
T Maschio-Lima, TH Lemes, MDR Marques… - International …, 2024 - Springer
The scarce antifungal arsenal, changes in the susceptibility profile of fungal agents, and lack
of adherence to treatment have contributed to the increase of cases of dermatomycoses. In …
of adherence to treatment have contributed to the increase of cases of dermatomycoses. In …