Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk;
lifestyle and environmental factors are key contributors to the risk of MS. Importantly, these …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

Growing empirical evidence suggests that nutrition and bacterial metabolites might impact
the systemic immune response in the context of disease and autoimmunity. We report that …

Association studies have greatly refined the understanding of how variation within the
human leukocyte antigen (HLA) genes influences risk of multiple sclerosis. However, the …

Clinically isolated syndrome (CIS) is a term that describes a first clinical episode with
features suggestive of multiple sclerosis (MS). It usually occurs in young adults and affects …

Shared aetiopathogenic factors among immune-mediated diseases have long been
suggested by their co-familiality and co-occurrence, and molecular support has been …

Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS),
because genetic predisposition only explains a fraction of the risk increase. There is strong …

In a Swedish population-based case-control study (1571 cases, 3371 controls), subjects
with different body mass indices (BMIs) were compared regarding multiple sclerosis (MS) …

The association between smoke habit and autoimmunity has been hypothesized a long time
ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it …

Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …