Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and
exogenous processes, and their negative effects are neutralized by antioxidant defenses …

This brief review summarizes the recently obtained evidence which illustrates the beneficial
effects of the endogenously produced antioxidant, melatonin, in reducing tissue damage …

Melatonin, acting through melatonin receptors, is involved in numerous physiological
processes including circadian entrainment, blood pressure regulation, oncogenesis, retinal …

Several melatonin receptors agonists (ramelteon, prolonged-release melatonin,
agomelatine and tasimelteon) have recently become available for the treatment of insomnia …

This review briefly summarizes the actions of melatonin in reducing molecular damage
caused by free radicals and associated oxygen-and nitrogenbased reactants. All the …

Melatonin, a well-known antioxidant, has been shown to protect against ischemia-
reperfusion myocardial damage. Mitochondrial permeability transition pore (MPTP) opening …

Melatonin is a ubiquitous natural neurotransmitter-like compound produced primarily by the
pineal gland. This agent is involved in numerous aspects of the biological and physiologic …

Obesity, a major risk factor for ischemic heart disease, is associated with increased oxidative
stress and reduced antioxidant status. Melatonin, a potent free radical scavenger and …

The metabolic syndrome (M et S) is a cluster of metabolic abnormalities associated with
increased risk for cardiovascular diseases. Apart from its powerful antioxidant properties, the …

Objective—Widespread death of implanted cells hampers stem cell therapy for acute
myocardial infarction (AMI). Based on the pleiotropic beneficial effects of statins, we …